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@article{1369490,
author = {Havranek, S. and Fiala, Martin and Bulava, A. and Sknouril, L. and Dorda, M. and Bulkova, V. and Fingrova, Z. and Souckova, L. and Palecek, T. and Simek, J. and Linhart, A. and Wichterle, D.},
article_location = {San Francisco},
article_number = {3},
doi = {http://dx.doi.org/10.1371/journal.pone.0152553},
keywords = {Echocardiography; 3-Dimensional Electroanatomic Mapping; Atrial Fibrillation},
language = {eng},
issn = {1932-6203},
journal = {Plos one},
title = {Multivariate Analysis of Correspondence between Left Atrial Volumes Assessed by Echocardiography and 3-Dimensional Electroanatomic Mapping in Patients with Atrial Fibrillation},
volume = {11},
year = {2016}
}
TY - JOUR
ID - 1369490
AU - Havranek, S. - Fiala, Martin - Bulava, A. - Sknouril, L. - Dorda, M. - Bulkova, V. - Fingrova, Z. - Souckova, L. - Palecek, T. - Simek, J. - Linhart, A. - Wichterle, D.
PY - 2016
TI - Multivariate Analysis of Correspondence between Left Atrial Volumes Assessed by Echocardiography and 3-Dimensional Electroanatomic Mapping in Patients with Atrial Fibrillation
JF - Plos one
VL - 11
IS - 3
SP - "e0152553"
EP - "e0152553"
PB - Public Library of Science
SN - 19326203
KW - Echocardiography
KW - 3-Dimensional Electroanatomic Mapping
KW - Atrial Fibrillation
N2 - Background Left atrial (LA) enlargement is a predictor of worse outcome after catheter ablation for atrial fibrillation (AF). Widely used two-dimensional (2D)-echocardiography is inaccurate and underestimates real LA volume (LAV). We hypothesized that baseline clinical characteristics of patients can be used to adjust 2D-ECHO indices of LAV in order to minimize this disagreement. Methods The study enrolled 535 patients (59 +/- 9 years; 67% males; 43% paroxysmal AF) who underwent catheter ablation for AF in three specialized centers. We investigated multivariately the relationship between 2D-echocardiographic indices of LA size, specifically LA diameter in M-mode in the parasternal long-axis view (LAD), LAV assessed by the prolate-ellipsoid method (LAV(Ellipsoid)), LAV by the planimetric method (LAV(Planimetry)), and LAV derived from 3D-electroanatomic mapping (LAV(CARTO)). Results Cubed LAD of 106 +/- 45 ml, LAV(Ellipsoid) of 72 +/- 24 ml and LAV(Planimetry) of 88 +/- 30 ml correlated only modestly (r = 0.60, 0.69, and 0.53, respectively) with LAV(CARTO) of 137 +/- 46 ml, which was significantly underestimated with a bias (+/- 1.96 standard deviation) of -31 (-111; +49) ml, -64(-132; +2) ml, and -49(-125; +27) ml, respectively; p < 0.0001 for their mutual difference. LA enlargement itself, age, gender, type of AF, and the presence of structural heart disease were independent confounders of measurement error of 2D-echocardiographic LAV. Conclusion Accuracy and precision of all 2D-echocardiographic LAV indices are poor. Their agreement with true LAV can be significantly improved by multivariate adjustment to clinical characteristics of patients.
ER -
HAVRANEK, S., Martin FIALA, A. BULAVA, L. SKNOURIL, M. DORDA, V. BULKOVA, Z. FINGROVA, L. SOUCKOVA, T. PALECEK, J. SIMEK, A. LINHART and D. WICHTERLE. Multivariate Analysis of Correspondence between Left Atrial Volumes Assessed by Echocardiography and 3-Dimensional Electroanatomic Mapping in Patients with Atrial Fibrillation. \textit{Plos one}. San Francisco: Public Library of Science, 2016, vol.~11, No~3, p.~''e0152553'', 12 pp. ISSN~1932-6203. Available from: https://dx.doi.org/10.1371/journal.pone.0152553.
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