J 2017

A novel method for heterocyclic amide–thioamide transformations

HASSAN, Walid Fathalla M., Ibrahim A. I. ALI and Pavel PAZDERA

Basic information

Original name

A novel method for heterocyclic amide–thioamide transformations

Authors

HASSAN, Walid Fathalla M. (818 Egypt, belonging to the institution), Ibrahim A. I. ALI (818 Egypt) and Pavel PAZDERA (203 Czech Republic, guarantor, belonging to the institution)

Edition

Beilstein Journal of Organic Chemistry, 2017, 1860-5397

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10401 Organic chemistry

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 2.330

RIV identification code

RIV/00216224:14310/17:00096105

Organization unit

Faculty of Science

DOI

UT WoS

000395042800001

Keywords in English

heterocyclic amides; heterocyclic thioamides; N-cyclohexyl dithiocarbamate cyclohexylammonium salt; novel thiating agent; thiation

Tags

Změněno: 27/3/2018 16:16, Ing. Nicole Zrilić

Abstract

V originále

In this paper, we introduce a novel and convenient method for the transformation of heterocyclic amides into heteocyclic thioamides. A two-step approach was applied for this transformation: Firstly, we applied a chlorination of the heterocyclic amides to afford the corresponding chloroheterocycles. Secondly, the chloroherocycles and N-cyclohexyl dithiocarbamate cyclohexylammonium salt were heated in chloroform for 12 h at 61 °C to afford heteocyclic thioamides in excellent yields.