Lokální anestetika v klinické praxi

VERNEROVÁ, Eva, Sáva PEŠÁK and Vojtěch THON. Lokální anestetika v klinické praxi (Local anesthetics in clinical praxis). Bolest. Praha: Tigis, 2016, vol. 19, No 2, p. 60-62. ISSN 1212-0634.

Basic information

• Original name: Lokální anestetika v klinické praxi
• Name (in English): Local anesthetics in clinical praxis
• Authors: VERNEROVÁ, Eva (203 Czech Republic), Sáva PEŠÁK (203 Czech Republic) and Vojtěch THON (203 Czech Republic, guarantor, belonging to the institution).
• Edition: Bolest, Praha, Tigis, 2016, 1212-0634.

Other information

• Original language: Czech
• Type of outcome: Article in a journal
• Field of Study: 30102 Immunology
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14110/16:00093388
• Organization unit: Faculty of Medicine
• Keywords in English: Adverse effects; Amide-type anesthetics; Ester-type anesthetics; Local anaesthetics
• Tags: EL OK
• Tags: International impact, Reviewed

Abstract

Lokální anestetika v klinické praxi. Lokální anestetika v klinické praxi

Abstract (in English)

Adverse reactions due to application of local anesthetics (LA) are quite often an indication to allergological examination. These reactions are much more farmacological, toxic or vasovagal nature, than really allergic, mediated by immunological mechanisms. Allergy to LA constitutes just 1% of all adverse reactions associated with an application of LA and fears concerning their heavy progress are not supported. Skin tests, i.e. skin prick tests as well as intradermal tests have very low specificity and sensitivity and their negativity is not a guaranty of subsequent tolerance of tested medicament. Therefore the correct diagnosis can only be established by incremental subcutaneous reintroduction of LA during carefully conducted and monitored challenge test. Such test is safe and usually well tolerated.