Metallothionein modulation in relation to cadmium
bioaccumulation and age-dependent sensitivity of Chironomus
riparius larvae

J 2016

Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae

TOUŠOVÁ, Zuzana, Jan KUTA, David HYNEK, Vojtěch ADAM, René KIZEK et. al.

Basic information

Original name

Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae

Authors

TOUŠOVÁ, Zuzana (203 Czech Republic, belonging to the institution), Jan KUTA (203 Czech Republic, belonging to the institution), David HYNEK (203 Czech Republic), Vojtěch ADAM (203 Czech Republic), René KIZEK (203 Czech Republic), Luděk BLÁHA (203 Czech Republic, belonging to the institution) and Klára HILSCHEROVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Environmental Science and Pollution Research, Landsberg, Germany, Ecomed, 2016, 0944-1344

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30304 Public and environmental health

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.741

RIV identification code

RIV/00216224:14310/16:00093481

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1007/s11356-016-6362-5

UT WoS

000377021500018

Keywords in English

Chironomus; Artificial sediment; Cadmium; Bioaccumulation; Metallothionein

Abstract

V originále

The goal of this study was to contribute to understanding of the mechanisms behind sensitivity differences between early and late instar larvae of Chironomus riparius and to address the influence of the differences in standard testing approaches on the toxicity evaluation. A 10-day contact sediment toxicity test was carried out to assess sensitivity to cadmium exposure in relation to different age and laboratory culture line origin of test organisms. Chironomid larvae of early (OECD 218 method) and late instar (US-EPA600/R-99/064 method) differed substantially in sensitivity of traditional endpoints (OECD: LOEC 50 and 10 mu g Cd/g dry weight (dw); US-EPA: LOEC > 1000 and 100 mu g Cd/g dw for survival and growth, respectively). Bioaccumulated cadmium and metallothioneins (MTs) concentrations were analyzed to investigate the role of MTs in reduced sensitivity to cadmium in late instar larvae. Metallothioneins were induced after treatment to greater Cd concentrations, but their levels in relation to cadmium body burdens did not fully explain low sensitivity of late instars to cadmium, which indicates some other effective way of detoxification in late instars. This study brings new information related to the role of MTs in age-dependent toxicant sensitivity and discusses the implications of divergence in data generated by chironomid sediment toxicity tests by standardized methods using different instars.

Links

LM2011028, research and development project

Name: RECETOX ? Národní infrastruktura pro výzkum toxických látek v prostředí

Investor: Ministry of Education, Youth and Sports of the CR

LO1214, research and development project

Name: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

TOUŠOVÁ, Zuzana, Jan KUTA, David HYNEK, Vojtěch ADAM, René KIZEK, Luděk BLÁHA and Klára HILSCHEROVÁ. Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae. Environmental Science and Pollution Research. Landsberg, Germany: Ecomed, 2016, vol. 23, No 11, p. 10504-10513. ISSN 0944-1344. Available from: https://dx.doi.org/10.1007/s11356-016-6362-5.

@article{1371972,
   author = {Toušová, Zuzana and Kuta, Jan and Hynek, David and Adam, Vojtěch and Kizek, René and Bláha, Luděk and Hilscherová, Klára},
   article_location = {Landsberg, Germany},
   article_number = {11},
   doi = {http://dx.doi.org/10.1007/s11356-016-6362-5},
   keywords = {Chironomus; Artificial sediment; Cadmium; Bioaccumulation; Metallothionein},
   language = {eng},
   issn = {0944-1344},
   journal = {Environmental Science and Pollution Research},
   title = {Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae},
   url = {http://link.springer.com/article/10.1007%2Fs11356-016-6362-5},
   volume = {23},
   year = {2016}
}

TY  - JOUR
ID  - 1371972
AU  - Toušová, Zuzana - Kuta, Jan - Hynek, David - Adam, Vojtěch - Kizek, René - Bláha, Luděk - Hilscherová, Klára
PY  - 2016
TI  - Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae
JF  - Environmental Science and Pollution Research
VL  - 23
IS  - 11
SP  - 10504-10513
EP  - 10504-10513
PB  - Ecomed
SN  - 09441344
KW  - Chironomus
KW  - Artificial sediment
KW  - Cadmium
KW  - Bioaccumulation
KW  - Metallothionein
UR  - http://link.springer.com/article/10.1007%2Fs11356-016-6362-5
L2  - http://link.springer.com/article/10.1007%2Fs11356-016-6362-5
N2  - The goal of this study was to contribute to understanding of the mechanisms behind sensitivity differences between early and late instar larvae of Chironomus riparius and to address the influence of the differences in standard testing approaches on the toxicity evaluation. A 10-day contact sediment toxicity test was carried out to assess sensitivity to cadmium exposure in relation to different age and laboratory culture line origin of test organisms. Chironomid larvae of early (OECD 218 method) and late instar (US-EPA600/R-99/064 method) differed substantially in sensitivity of traditional endpoints (OECD: LOEC 50 and 10 mu g Cd/g dry weight (dw); US-EPA: LOEC > 1000 and 100 mu g Cd/g dw for survival and growth, respectively). Bioaccumulated cadmium and metallothioneins (MTs) concentrations were analyzed to investigate the role of MTs in reduced sensitivity to cadmium in late instar larvae. Metallothioneins were induced after treatment to greater Cd concentrations, but their levels in relation to cadmium body burdens did not fully explain low sensitivity of late instars to cadmium, which indicates some other effective way of detoxification in late instars. This study brings new information related to the role of MTs in age-dependent toxicant sensitivity and discusses the implications of divergence in data generated by chironomid sediment toxicity tests by standardized methods using different instars.
ER  -

TOUŠOVÁ, Zuzana, Jan KUTA, David HYNEK, Vojtěch ADAM, René KIZEK, Luděk BLÁHA and Klára HILSCHEROVÁ. Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae. \textit{Environmental Science and Pollution Research}. Landsberg, Germany: Ecomed, 2016, vol.~23, No~11, p.~10504-10513. ISSN~0944-1344. Available from: https://dx.doi.org/10.1007/s11356-016-6362-5.

Detailed Information on Publication Record