TOUŠOVÁ, Zuzana, Jan KUTA, David HYNEK, Vojtěch ADAM, René KIZEK, Luděk BLÁHA and Klára HILSCHEROVÁ. Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae. Environmental Science and Pollution Research. Landsberg, Germany: Ecomed, vol. 23, No 11, p. 10504-10513. ISSN 0944-1344. doi:10.1007/s11356-016-6362-5. 2016.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Metallothionein modulation in relation to cadmium bioaccumulation and age-dependent sensitivity of Chironomus riparius larvae
Authors TOUŠOVÁ, Zuzana (203 Czech Republic, belonging to the institution), Jan KUTA (203 Czech Republic, belonging to the institution), David HYNEK (203 Czech Republic), Vojtěch ADAM (203 Czech Republic), René KIZEK (203 Czech Republic), Luděk BLÁHA (203 Czech Republic, belonging to the institution) and Klára HILSCHEROVÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition Environmental Science and Pollution Research, Landsberg, Germany, Ecomed, 2016, 0944-1344.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30304 Public and environmental health
Country of publisher Germany
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 2.741
RIV identification code RIV/00216224:14310/16:00093481
Organization unit Faculty of Science
Doi http://dx.doi.org/10.1007/s11356-016-6362-5
UT WoS 000377021500018
Keywords in English Chironomus; Artificial sediment; Cadmium; Bioaccumulation; Metallothionein
Tags AKR, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Michaela Hylsová, Ph.D., učo 211937. Changed: 2/3/2017 12:23.
Abstract
The goal of this study was to contribute to understanding of the mechanisms behind sensitivity differences between early and late instar larvae of Chironomus riparius and to address the influence of the differences in standard testing approaches on the toxicity evaluation. A 10-day contact sediment toxicity test was carried out to assess sensitivity to cadmium exposure in relation to different age and laboratory culture line origin of test organisms. Chironomid larvae of early (OECD 218 method) and late instar (US-EPA600/R-99/064 method) differed substantially in sensitivity of traditional endpoints (OECD: LOEC 50 and 10 mu g Cd/g dry weight (dw); US-EPA: LOEC > 1000 and 100 mu g Cd/g dw for survival and growth, respectively). Bioaccumulated cadmium and metallothioneins (MTs) concentrations were analyzed to investigate the role of MTs in reduced sensitivity to cadmium in late instar larvae. Metallothioneins were induced after treatment to greater Cd concentrations, but their levels in relation to cadmium body burdens did not fully explain low sensitivity of late instars to cadmium, which indicates some other effective way of detoxification in late instars. This study brings new information related to the role of MTs in age-dependent toxicant sensitivity and discusses the implications of divergence in data generated by chironomid sediment toxicity tests by standardized methods using different instars.
Links
LM2011028, research and development projectName: RECETOX ? Národní infrastruktura pro výzkum toxických látek v prostředí
Investor: Ministry of Education, Youth and Sports of the CR
LO1214, research and development projectName: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX)
Investor: Ministry of Education, Youth and Sports of the CR
PrintDisplayed: 29/3/2024 16:20