Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts - Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring

DI PAOLO, Carolina, Richard OTTERMANNS, Steffen KEITER, Selim AIT-AISSA, Kerstin BLUHM, Werner BRACK, Magnus BREITHOLTZ, Sebastian BUCHINGER, Mario CARERE, Carole CHALON, Xavier COUSIN, Valeria DULIO, Beate I. ESCHER, Timo HAMERS, Klára HILSCHEROVÁ, Sergio JARQUE ORTIZ, Adam JONÁŠ, Emmanuelle MAILLOT-MARECHAL, Yves MARNEFFE, Mai Thao NGUYEN, Pascal PANDARD, Andrea SCHIFFERLI, Tobias SCHULZE, Sven SEIDENSTICKER, Thomas-Benjamin SEILER, Janet TANG, Ron VAN DER OOST, Etienne VERMEIRSSEN, Radka ZOUNKOVÁ, Nick ZWART and Henner HOLLERT. Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts - Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring. Online. Water Research. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2016, vol. 104, November, p. 473-484. ISSN 0043-1354. Available from: https://dx.doi.org/10.1016/j.watres.2016.08.018. [citováno 2024-04-23]

Basic information

• Original name: Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts - Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring
• Authors: DI PAOLO, Carolina (276 Germany), Richard OTTERMANNS (276 Germany), Steffen KEITER (276 Germany), Selim AIT-AISSA (250 France), Kerstin BLUHM (276 Germany), Werner BRACK (276 Germany), Magnus BREITHOLTZ (752 Sweden), Sebastian BUCHINGER (276 Germany), Mario CARERE (380 Italy), Carole CHALON (56 Belgium), Xavier COUSIN (250 France), Valeria DULIO (250 France), Beate I. ESCHER (276 Germany), Timo HAMERS (528 Netherlands), Klára HILSCHEROVÁ (203 Czech Republic, guarantor, belonging to the institution), Sergio JARQUE ORTIZ (724 Spain, belonging to the institution), Adam JONÁŠ (203 Czech Republic, belonging to the institution), Emmanuelle MAILLOT-MARECHAL (250 France), Yves MARNEFFE (56 Belgium), Mai Thao NGUYEN (528 Netherlands), Pascal PANDARD (250 France), Andrea SCHIFFERLI (756 Switzerland), Tobias SCHULZE (276 Germany), Sven SEIDENSTICKER (276 Germany), Thomas-Benjamin SEILER (276 Germany), Janet TANG (36 Australia), Ron VAN DER OOST (528 Netherlands), Etienne VERMEIRSSEN (756 Switzerland), Radka ZOUNKOVÁ (203 Czech Republic, belonging to the institution), Nick ZWART (528 Netherlands) and Henner HOLLERT (276 Germany)
• Edition: Water Research, OXFORD, PERGAMON-ELSEVIER SCIENCE LTD, 2016, 0043-1354.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30304 Public and environmental health
• Country of publisher: United Kingdom of Great Britain and Northern Ireland
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 6.942
• RIV identification code: RIV/00216224:14310/16:00093522
• Organization unit: Faculty of Science
• Doi: http://dx.doi.org/10.1016/j.watres.2016.08.018
• UT WoS: 000386401900049
• Keywords in English: Triclosan; Acridine; 17 alpha-ethinylestradiol; 3-Nitrobenzanthrone; Organism-level toxicity; Mechanism-specific toxicity
• Tags: AKR, rivok
• Tags: International impact, Reviewed

Abstract

Bioassays are particularly useful tools to link the chemical and ecological assessments in water quality monitoring. Different methods cover a broad range of toxicity mechanisms in diverse organisms, and account for risks posed by non-target compounds and mixtures. There is a need to address bioassay suitability to evaluate water samples containing emerging pollutants, which are a current priority in water quality monitoring. The presented interlaboratory study (ILS) verified whether a battery of miniaturized bioassays, conducted in 11 different laboratories following their own protocols, would produce comparable results when applied to evaluate blinded samples consisting of a pristine water extract spiked with four emerging pollutants as single chemicals or mixtures, i.e. triclosan, acridine, 17 alpha-ethinylestradiol (EE2) and 3-nitrobenzanthrone (3-NBA). Assays evaluated effects on aquatic organisms from three different trophic levels and mechanism-specific effects using in vitro estrogenicity and mutagenicity assays. The test battery presented complementary sensitivity and specificity to evaluate the different blinded water extract spikes. Estrogenicity and mutagenicity assays identified with high precision the respective mechanism-specific effects of spikes even when non-specific toxicity occurred in mixture. Differences in experimental protocols, model organisms, and data analysis can be sources of variation, indicating that respective harmonized standard procedures should be followed when implementing bioassays in water monitoring. Together with other ongoing activities for the validation of a basic bioassay battery, the present study is an important step towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring.

Links

• 603437, interní kód MU: Name: SOLUTIONS - Solutions for present and future emerging pollutants in land and water resources management (Acronym: SOLUTIONS)

Investor: European Union, Cooperation