MA, Jun, Jun-Jun HE, Guo-Hua LIU, Roman LEONTOVYČ, Martin KAŠNÝ and Xing-Quan ZHU. Complete mitochondrial genome of the giant liver fluke Fascioloides magna (Digenea: Fasciolidae) and its comparison with selected trematodes. PARASITES & VECTORS. BioMed Central, vol. 9, August, p. "nestrankovano", 7 pp. ISSN 1756-3305. doi:10.1186/s13071-016-1699-7. 2016.
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Basic information
Original name Complete mitochondrial genome of the giant liver fluke Fascioloides magna (Digenea: Fasciolidae) and its comparison with selected trematodes
Authors MA, Jun (156 China), Jun-Jun HE (156 China), Guo-Hua LIU (156 China), Roman LEONTOVYČ (203 Czech Republic), Martin KAŠNÝ (203 Czech Republic, guarantor, belonging to the institution) and Xing-Quan ZHU (156 China).
Edition PARASITES & VECTORS, BioMed Central, 2016, 1756-3305.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30309 Tropical medicine
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 3.035
RIV identification code RIV/00216224:14310/16:00093533
Organization unit Faculty of Science
Doi http://dx.doi.org/10.1186/s13071-016-1699-7
UT WoS 000381193700001
Keywords in English Fascioloides magna; Fasciola; Mitochondrial genome; Phylogenetic analysis
Tags AKR, rivok
Changed by Changed by: Mgr. Lucie Jarošová, DiS., učo 205746. Changed: 6/3/2018 14:36.
Abstract
Background: Representatives of the trematode family Fasciolidae are responsible for major socio-economic losses worldwide. Fascioloides magna is an important pathogenic liver fluke of wild and domestic ungulates. To date, only a limited number of studies concerning the molecular biology of F. magna exist. Therefore, the objective of the present study was to determine the complete mitochondrial (mt) genome sequence of F. magna, and assess the phylogenetic relationships of this fluke with other trematodes based on the mtDNA dataset. Findings: The complete F. magna mt genome sequence is 14,047 bp. The gene content and arrangement of the F. magna mt genome is similar to those of Fasciola spp., except that trnE is located between trnG and the only non-coding region in F. magna mt genome. Phylogenetic relationships of F. magna with selected trematodes using Bayesian inference (BI) was reconstructed based on the concatenated amino acid sequences for 12 protein-coding genes, which confirmed that the genus Fascioloides is closely related to the genus Fasciola; the intergeneric differences of amino acid composition between the genera Fascioloides and Fasciola ranged 17.97-18.24 %. Conclusions: The determination of F. magna mt genome sequence provides a valuable resource for further investigations of the phylogeny of the family Fasciolidae and other trematodes, and represents a useful platform for designing appropriate molecular markers.
Links
MUNI/A/1325/2015, interní kód MUName: Analýzy diverzity biologických systémů různých úrovní a na různých škálách prostředí (Acronym: BIDA5)
Investor: Masaryk University, Category A
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