Detailed Information on Publication Record
2017
Biocompatibility of NiTi alloys in the cell behaviour
ŠEVČÍKOVÁ, Jana and Monika PÁVKOVÁ GOLDBERGOVÁBasic information
Original name
Biocompatibility of NiTi alloys in the cell behaviour
Authors
ŠEVČÍKOVÁ, Jana (203 Czech Republic, belonging to the institution) and Monika PÁVKOVÁ GOLDBERGOVÁ (203 Czech Republic, guarantor, belonging to the institution)
Edition
BioMetals, Dordrecht, Springer, 2017, 0966-0844
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10608 Biochemistry and molecular biology
Country of publisher
Netherlands
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 2.478
RIV identification code
RIV/00216224:14110/17:00094656
Organization unit
Faculty of Medicine
UT WoS
000398709100002
Keywords in English
Alloy; Biocompatibility; Biomaterial; Cell; NiTi
Tags
Tags
International impact, Reviewed
Změněno: 20/3/2018 18:20, Soňa Böhmová
Abstract
V originále
Metallic biomaterial alloys composed of nickel and titanium have unique thermal shape memory, superelastic, and high damping properties, which are widely used in the medicine. The major parameter evaluated in the studies regarding the behaviour of the material in the contact with organism or cells is biocompatibility. The aim of the studies is to clarify the differences in the proliferation, growth, and morphology especially in the cell cultures. The cytotoxicity is affected among other by release of the metal ions in the presence of the metal alloy, which is further dependent on the possible treatments of the material and the corrosive properties. To evaluate the cytotoxicity, wide range of tests including the Sulforhodamine B assay and MTT tests, expression profiles, cell survival tests such as apoptotic test are used. The review compares the cell behaviour in contact with the material alloys composed of nickel and titanium with respect to different materials composition and different surface treatment that affects the ion release. Even though the results published so far are controversial, almost all data suggest sufficient biocompatibility in medical use.
Links
| GA15-16336S, research and development project |
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