PALÍKOVÁ, Miroslava, Ivana PAPEŽÍKOVÁ, Zdeňka MARKOVÁ, Stanislav NAVRÁTIL, Jan MAREŠ, Lukáš MAREŠ, Libor VOJTEK, Pavel HYRŠL, Eva JELÍNKOVÁ a Heike SCHMIDT-POSTHAUS. Proliferative kidney disease in rainbow trout (Oncorhynchus mykiss) under intensive breeding conditions: Pathogenesis and haematological and immune parameters. Veterinary Parasitology. Amsterdam: Elsevier Science, roč. 238, April, s. 5-16. ISSN 0304-4017. doi:10.1016/j.vetpar.2017.03.003. 2017.
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Základní údaje
Originální název Proliferative kidney disease in rainbow trout (Oncorhynchus mykiss) under intensive breeding conditions: Pathogenesis and haematological and immune parameters
Autoři PALÍKOVÁ, Miroslava (203 Česká republika, garant), Ivana PAPEŽÍKOVÁ (203 Česká republika), Zdeňka MARKOVÁ (203 Česká republika), Stanislav NAVRÁTIL (203 Česká republika), Jan MAREŠ (203 Česká republika), Lukáš MAREŠ (203 Česká republika), Libor VOJTEK (203 Česká republika, domácí), Pavel HYRŠL (203 Česká republika, domácí), Eva JELÍNKOVÁ (203 Česká republika) a Heike SCHMIDT-POSTHAUS (756 Švýcarsko).
Vydání Veterinary Parasitology, Amsterdam, Elsevier Science, 2017, 0304-4017.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30102 Immunology
Stát vydavatele Nizozemské království
Utajení není předmětem státního či obchodního tajemství
Impakt faktor Impact factor: 2.422
Kód RIV RIV/00216224:14310/17:00096260
Organizační jednotka Přírodovědecká fakulta
Doi http://dx.doi.org/10.1016/j.vetpar.2017.03.003
UT WoS 000403117800002
Klíčová slova česky Proliferativní onemocnění ledvin; pstruh duhový; oxidační vzplanutí; celkové imunoglobuliny; aktivita komplementu; histologie; imunochemie
Klíčová slova anglicky Proliferative kidney disease; Rainbow trout; Oxidative burst; Total immunoglobulins; Complement activity; Histology; Immunohistochemistry
Štítky NZ, rivok
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: Ing. Nicole Zrilić, učo 240776. Změněno: 10. 4. 2018 23:03.
Anotace
Proliferative kidney disease (PKD) is an endoparasitic disease of salmonid fish caused by Tetracapsuloides bryosalmonae (Myxozoa: Malacosporea). This study presents a comprehensive view on PKD development in rainbow trout (Oncorhynchus mykiss) reared at an intensive fish breeding facility, with focus on mortality, pathology/histopathology, haematological findings and immune functions. Diseased and reference fish were sampled monthly and time course of natural infection was followed up from the onset of clinical signs (September 2014) to full recovery (January 2015). PKD- associated cumulative mortality was 30% with a peak value in October, while immunohistochemical testing indicated a continuous significant decrease in T. bryosalmonae numbers from September to December; with no parasites detected in January. During peak clinical infection, a significant decrease in red blood cell counts, haematocrit values, haemoglobin concentration, along with a reduction in lymphocytes and a significant phagocyte elevation corresponding with an increase in phagocyte oxidative burst were measured in comparison to control animals. Complement activity and total immunoglobulin plasma concentrations were also elevated, though only during the initial monitoring period (September). Individuals surviving PKD, recovered and were able to fully regenerate both renal structure and haematopoietic parameters to normal levels. Changes in the red blood cell parameters indicate anaemia and a decreased oxygen transportation capacity during the clinical disease phase. Together with an increased oxygen demand at higher temperatures and decreased oxygen solubility this could lead to decompensation and elevated mortality. The stimulation of immune parameters, and especially oxidative phagocytic burst, is likely to have had a strong effect on both, regeneration and elimination of the pathogenic agent.
VytisknoutZobrazeno: 29. 3. 2024 12:56