Detailed Information on Publication Record
2016
LA-ICP-MS as a tool for imaging of tumour tissue
VACULOVIČ, Tomáš, Michaela TVRDOŇOVÁ, Michal MASAŘÍK, Hana POLANSKÁ, Markéta SVOBODOVÁ et. al.Basic information
Original name
LA-ICP-MS as a tool for imaging of tumour tissue
Authors
VACULOVIČ, Tomáš (203 Czech Republic, guarantor, belonging to the institution), Michaela TVRDOŇOVÁ (203 Czech Republic, belonging to the institution), Michal MASAŘÍK (203 Czech Republic, belonging to the institution), Hana POLANSKÁ (203 Czech Republic, belonging to the institution), Markéta SVOBODOVÁ (203 Czech Republic) and Viktor KANICKÝ (203 Czech Republic)
Edition
European Workshop on Laser Ablation, 2016
Other information
Language
English
Type of outcome
Prezentace na konferencích
Field of Study
10406 Analytical chemistry
Country of publisher
Slovenia
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14310/16:00093835
Organization unit
Faculty of Science
Keywords in English
laser-matter interaction; particle formation and transport phenomena; mapping strategies; standardization; isotope ratio analysis;
Tags
Tags
International impact
Změněno: 26/4/2017 23:16, Ing. Andrea Mikešková
Abstract
V originále
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) allows study of lateral distribution of specific elements (Cu, Zn, Pb, Pt) in very low concentration levels (mg/kg) in tumor tissues. Presented work is focused on study of laser ablation parameters (scan speed and laser spot diameter) on lateral resolution and limit of detection of LA-ICP-MS. The utilization of LA-ICP-MS for bioimaging purpose will be demonstrated on mice tumour tissues analysis which are treated by various Pt-based cytostatics (carbo-, oxali- and cis-Pt).
Links
| ED1.1.00/02.0068, research and development project |
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