Buccal films as a dressing for the treatment of aphthous
lesions

J 2017

Buccal films as a dressing for the treatment of aphthous lesions

DANĚK, Zdeněk, Jan GAJDZIOK, Petr DOLEŽEL, Hana LANDOVÁ, David VETCHÝ et. al.

Basic information

Original name

Buccal films as a dressing for the treatment of aphthous lesions

Authors

DANĚK, Zdeněk (203 Czech Republic, guarantor, belonging to the institution), Jan GAJDZIOK (203 Czech Republic), Petr DOLEŽEL (203 Czech Republic), Hana LANDOVÁ (203 Czech Republic), David VETCHÝ (203 Czech Republic) and Jan ŠTEMBÍREK (203 Czech Republic)

Edition

Journal of Oral Pathology & Medicine, Hoboken, Wiley-Blackwell, 2017, 0904-2512

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30208 Dentistry, oral surgery and medicine

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.237

RIV identification code

RIV/00216224:14110/17:00096270

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1111/jop.12563

UT WoS

000400193100010

Keywords in English

aphthous lesions; mucoadhesive buccal films; oral mucosa; pain reduction; residence time

Abstract

V originále

Background Buccal flexible films in the form of solid, thin, mucoadhesive patches can be used as dressings separating aphthous lesions from the environment of the oral cavity, which can in turn shorten the treatment period and reduce the pain perception. Methods The clinical study was performed on 36 volunteers suffering from aphthous lesions. The first group was treated using standard means—by application of an oral gel containing cholin salicylate (Mundisal) on the aphthous lesion. The second group was treated with the same preparation; however, the lesion was covered with a mucoadhesive film following the application of the gel. The criteria for statistical evaluation were the size of lesions in relation to the length of the treatment and the subjective perception of the treatment results. Results and conclusions The application of buccal films covering aphthous lesions during the treatment significantly increased the rate of healing when compared with the standard methods of treatment. While the pain improvement was statistically significant as soon as Day 3 in the experimental group, it was only apparent on Day 5 in the control group, and the number of successfully treated patients (pain perception improving to visual analogue scale 2 or less) was at all time points higher in the experimental group than in the control group. The results imply that the use of buccal films for treatment of aphthous lesions is very promising and can lead to a significant reduction in the duration of patients’ discomfort.

Citovat

DANĚK, Zdeněk, Jan GAJDZIOK, Petr DOLEŽEL, Hana LANDOVÁ, David VETCHÝ and Jan ŠTEMBÍREK. Buccal films as a dressing for the treatment of aphthous lesions. Journal of Oral Pathology & Medicine. Hoboken: Wiley-Blackwell, 2017, vol. 46, No 4, p. 301-306. ISSN 0904-2512. Available from: https://dx.doi.org/10.1111/jop.12563.

@article{1375079,
   author = {Daněk, Zdeněk and Gajdziok, Jan and Doležel, Petr and Landová, Hana and Vetchý, David and Štembírek, Jan},
   article_location = {Hoboken},
   article_number = {4},
   doi = {http://dx.doi.org/10.1111/jop.12563},
   keywords = {aphthous lesions; mucoadhesive buccal films; oral mucosa; pain reduction; residence time},
   language = {eng},
   issn = {0904-2512},
   journal = {Journal of Oral Pathology & Medicine},
   title = {Buccal films as a dressing for the treatment of aphthous lesions},
   volume = {46},
   year = {2017}
}

TY  - JOUR
ID  - 1375079
AU  - Daněk, Zdeněk - Gajdziok, Jan - Doležel, Petr - Landová, Hana - Vetchý, David - Štembírek, Jan
PY  - 2017
TI  - Buccal films as a dressing for the treatment of aphthous lesions
JF  - Journal of Oral Pathology & Medicine
VL  - 46
IS  - 4
SP  - 301-306
EP  - 301-306
PB  - Wiley-Blackwell
SN  - 09042512
KW  - aphthous lesions
KW  - mucoadhesive buccal films
KW  - oral mucosa
KW  - pain reduction
KW  - residence time
N2  - Background Buccal flexible films in the form of solid, thin, mucoadhesive patches can be used as dressings separating aphthous lesions from the environment of the oral cavity, which can in turn shorten the treatment period and reduce the pain perception. Methods The clinical study was performed on 36 volunteers suffering from aphthous lesions. The first group was treated using standard means—by application of an oral gel containing cholin salicylate (Mundisal) on the aphthous lesion. The second group was treated with the same preparation; however, the lesion was covered with a mucoadhesive film following the application of the gel. The criteria for statistical evaluation were the size of lesions in relation to the length of the treatment and the subjective perception of the treatment results. Results and conclusions The application of buccal films covering aphthous lesions during the treatment significantly increased the rate of healing when compared with the standard methods of treatment. While the pain improvement was statistically significant as soon as Day 3 in the experimental group, it was only apparent on Day 5 in the control group, and the number of successfully treated patients (pain perception improving to visual analogue scale 2 or less) was at all time points higher in the experimental group than in the control group. The results imply that the use of buccal films for treatment of aphthous lesions is very promising and can lead to a significant reduction in the duration of patients’ discomfort.
ER  -

DANĚK, Zdeněk, Jan GAJDZIOK, Petr DOLEŽEL, Hana LANDOVÁ, David VETCHÝ and Jan ŠTEMBÍREK. Buccal films as a dressing for the treatment of aphthous lesions. \textit{Journal of Oral Pathology \&{} Medicine}. Hoboken: Wiley-Blackwell, 2017, vol.~46, No~4, p.~301-306. ISSN~0904-2512. Available from: https://dx.doi.org/10.1111/jop.12563.

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