| LACINA, Karel, Jaromír ŽÁK, Jakub SOPOUŠEK, Zoltán SZABÓ, Tomáš VÁCLAVEK, Jiří ŽERAVÍK, Pavel FIALA and Petr SKLÁDAL. Transistor Amplifier as an Electrochemical Transducer with Intuitive Optical Read-out: Improving Its Performance with Simple Electronic Solutions. Electrochimica Acta. Oxford: PERGAMON-ELSEVIER SCIENCE LTD, 2016, vol. 216, October, p. 147-151. ISSN 0013-4686. Available from: https://dx.doi.org/10.1016/j.electacta.2016.09.028. |
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@article{1375540,
author = {Lacina, Karel and Žák, Jaromír and Sopoušek, Jakub and Szabó, Zoltán and Václavek, Tomáš and Žeravík, Jiří and Fiala, Pavel and Skládal, Petr},
article_location = {Oxford},
article_number = {October},
doi = {http://dx.doi.org/10.1016/j.electacta.2016.09.028},
keywords = {Electrochemical transducer; transistor; operational amplifier; optical read-out; (bio)sensing},
language = {eng},
issn = {0013-4686},
journal = {Electrochimica Acta},
title = {Transistor Amplifier as an Electrochemical Transducer with Intuitive Optical Read-out: Improving Its Performance with Simple Electronic Solutions},
url = {http://dx.doi.org/10.1016/j.electacta.2016.09.028},
volume = {216},
year = {2016}
}
TY - JOUR
ID - 1375540
AU - Lacina, Karel - Žák, Jaromír - Sopoušek, Jakub - Szabó, Zoltán - Václavek, Tomáš - Žeravík, Jiří - Fiala, Pavel - Skládal, Petr
PY - 2016
TI - Transistor Amplifier as an Electrochemical Transducer with Intuitive Optical Read-out: Improving Its Performance with Simple Electronic Solutions
JF - Electrochimica Acta
VL - 216
IS - October
SP - 147-151
EP - 147-151
PB - PERGAMON-ELSEVIER SCIENCE LTD
SN - 00134686
KW - Electrochemical transducer
KW - transistor
KW - operational amplifier
KW - optical read-out
KW - (bio)sensing
UR - http://dx.doi.org/10.1016/j.electacta.2016.09.028
L2 - http://dx.doi.org/10.1016/j.electacta.2016.09.028
N2 - A platform for electrochemical transduction suitable for miniaturised point-of-care diagnostic solutions with intuitive optical read-out was designed. Electrolytic current from electrochemical cell was transduced into the glow of a light-emitting diode. Its performance was optimised and several variants of transducing circuitry were tested. The circuit comprising field-effect transistor (FET) exhibited the sought abilities - absolute simplicity and high and tuneable sensitivity of the transducing device. Limit-ofdetection, i.e. a signal readable by naked-eye without any additional instrumentation was as low as 4 mM for direct assay of H2O2. The whole transducing system employing FET consisted of 4 off-the-shelf components and its price reached <0.3 s even at small-scale experimental production. As our system was rather suitable for the semiquantitative “YES/NO” applications due to the steep response curve, an alternative circuitry for widening the linear range was also probed. Finally, rather higher initial voltage that was required in the electrochemical cell for FET-based transducer lead us to design a further simplified and more variable circuit employing the operational amplifier.
ER -
LACINA, Karel, Jaromír ŽÁK, Jakub SOPOUŠEK, Zoltán SZABÓ, Tomáš VÁCLAVEK, Jiří ŽERAVÍK, Pavel FIALA and Petr SKLÁDAL. Transistor Amplifier as an Electrochemical Transducer with Intuitive Optical Read-out: Improving Its Performance with Simple Electronic Solutions. \textit{Electrochimica Acta}. Oxford: PERGAMON-ELSEVIER SCIENCE LTD, 2016, vol.~216, October, p.~147-151. ISSN~0013-4686. Available from: https://dx.doi.org/10.1016/j.electacta.2016.09.028.
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