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@article{1375593,
author = {Mikalová, Lenka and Strouhal, Michal and Oppelt, Jan and Grange, Philippe Alain and Janier, Michel and Benhaddou, Nadjet and Dupin, Nicolas and Šmajs, David},
article_location = {San Francisco},
article_number = {3},
doi = {http://dx.doi.org/10.1371/journal.pntd.0005434},
keywords = {Treponema pallidum},
language = {eng},
issn = {1935-2735},
journal = {PLoS neglected tropical diseases},
title = {Human Treponema pallidum 11q/j isolate belongs to subsp. endemicum but contains two loci with a sequence in TP0548 and TP0488 similar to subsp. pertenue and subsp. pallidum, respectively},
url = {http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005434},
volume = {11},
year = {2017}
}
TY - JOUR
ID - 1375593
AU - Mikalová, Lenka - Strouhal, Michal - Oppelt, Jan - Grange, Philippe Alain - Janier, Michel - Benhaddou, Nadjet - Dupin, Nicolas - Šmajs, David
PY - 2017
TI - Human Treponema pallidum 11q/j isolate belongs to subsp. endemicum but contains two loci with a sequence in TP0548 and TP0488 similar to subsp. pertenue and subsp. pallidum, respectively
JF - PLoS neglected tropical diseases
VL - 11
IS - 3
SP - 1-14
EP - 1-14
PB - Public Library of Science
SN - 19352735
KW - Treponema pallidum
UR - http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005434
N2 - The TEN 11q/j isolate was characterized using nested PCR followed by Sanger sequencing and/or direct Illumina sequencing. Altogether, 44 chromosomal regions were analyzed. Overall, the 11q/j isolate clustered with TEN strains Bosnia A and Iraq B as expected from previous TEN classification of the 11q/j isolate. However, the 11q/j sequence in a 505 bp-long region at the TP0488 locus was similar to Treponema pallidum subsp. pallidum (TPA) strains, but not to TEN Bosnia A and Iraq B sequences, suggesting a recombination event at this locus. Similarly, the 11q/j sequence in a 613 bp-long region at the TP0548 locus was similar to Treponema pallidum subsp. pertenue (TPE) strains, but not to TEN sequences.
ER -
MIKALOVÁ, Lenka, Michal STROUHAL, Jan OPPELT, Philippe Alain GRANGE, Michel JANIER, Nadjet BENHADDOU, Nicolas DUPIN and David ŠMAJS. Human Treponema pallidum 11q/j isolate belongs to subsp. endemicum but contains two loci with a sequence in TP0548 and TP0488 similar to subsp. pertenue and subsp. pallidum, respectively. \textit{PLoS neglected tropical diseases}. San Francisco: Public Library of Science, 2017, vol.~11, No~3, p.~1-14. ISSN~1935-2735. Available from: https://dx.doi.org/10.1371/journal.pntd.0005434.
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