JANOUTOVÁ, Jana, Petra JANÁČKOVÁ, Omar ŠERÝ, Tomáš ZEMAN, Petr AMBROZ, Martina KOVALOVÁ, Kateřina VAŘECHOVÁ, Ladislav HOSÁK, Vítězslav JIŘÍK and Vladimír JANOUT. Epidemiology and risk factors of Schizophrenia. Neuroendocrinology Letters. Edition Medizin, 2016, vol. 37, No 1, p. 1-8. ISSN 0172-780X.
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Basic information
Original name Epidemiology and risk factors of Schizophrenia
Authors JANOUTOVÁ, Jana (203 Czech Republic), Petra JANÁČKOVÁ (203 Czech Republic), Omar ŠERÝ (203 Czech Republic, guarantor, belonging to the institution), Tomáš ZEMAN (203 Czech Republic, belonging to the institution), Petr AMBROZ (203 Czech Republic), Martina KOVALOVÁ (203 Czech Republic), Kateřina VAŘECHOVÁ (203 Czech Republic), Ladislav HOSÁK (203 Czech Republic), Vítězslav JIŘÍK (203 Czech Republic) and Vladimír JANOUT (203 Czech Republic).
Edition Neuroendocrinology Letters, Edition Medizin, 2016, 0172-780X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Sweden
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.918
RIV identification code RIV/00216224:14310/16:00093958
Organization unit Faculty of Science
UT WoS 000373446900001
Keywords in English Epidemiology; Genetic; Incidence; Prevalence; Risk factors; Schizophrenia
Tags AKR, rivok
Changed by Changed by: Ing. Andrea Mikešková, učo 137293. Changed: 5/4/2017 17:59.
Abstract
Schizophrenia is a severe mental disorder that affects approximately one percent of the general population. The pathogenesis of schizophrenia is influenced by many risk factors, both environmental and genetic. The environmental factors include the date of birth, place of birth and seasonal effects, infectious diseases, complications during pregnancy and delivery, substance abuse and stress. At the present time, in addition to environmental factors, genetic factors are assumed to play a role in the development of the schizophrenia. The heritability of schizophrenia is up to 80%. If one parent suffers from the condition, the probability that it will be passed down to the offspring is 13%. If it is present in both parents, the risk is more than 20%. The opinions are varied as to the risk factors affecting the development of schizophrenia. Knowing these factors may greatly contribute to prevention of the condition.
Links
MUNI/A/1265/2015, interní kód MUName: Podpora biochemického výzkumu v roce 2016
Investor: Masaryk University, Category A
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