GESCHEIDT, Tomáš, Veronika Ibarburu L. Y. LOSADA, Kateřina MENŠÍKOVÁ, Ladislav DUŠEK, Kristína CZEKÓOVÁ, Petra MENCLOVÁ, Petr KAŇOVSKÝ, Jan ROTH and Martin BAREŠ. Impulse control disorders in patients with young-onset Parkinson's disease: A cross-sectional study seeking associated factors. Basal Ganglia. Munich: Elsevier GmbH, 2016, vol. 6, No 4, p. 197-205. ISSN 2210-5336. Available from: https://dx.doi.org/10.1016/j.baga.2016.09.001.
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Basic information
Original name Impulse control disorders in patients with young-onset Parkinson's disease: A cross-sectional study seeking associated factors
Authors GESCHEIDT, Tomáš (203 Czech Republic), Veronika Ibarburu L. Y. LOSADA (203 Czech Republic), Kateřina MENŠÍKOVÁ (203 Czech Republic), Ladislav DUŠEK (203 Czech Republic, belonging to the institution), Kristína CZEKÓOVÁ (703 Slovakia, belonging to the institution), Petra MENCLOVÁ (203 Czech Republic), Petr KAŇOVSKÝ (203 Czech Republic), Jan ROTH (203 Czech Republic) and Martin BAREŠ (203 Czech Republic, guarantor, belonging to the institution).
Edition Basal Ganglia, Munich, Elsevier GmbH, 2016, 2210-5336.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Germany
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/16:00088955
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.baga.2016.09.001
UT WoS 000389532600004
Keywords in English Parkinson's disease; Impulse control disorders; Pathological gambling; Dopamine agonists; Personality
Tags EL OK, podil
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 27/3/2017 08:34.
Abstract
Introduction: The aim of this cross-sectional study was to investigate the frequency and factors associated with impulse control disorder (ICD) symptoms, including personality characteristics, in Czech young-onset Parkinson's disease (PD) patients. Subjects and methods: We examined 49 young-onset PD patients and 38 age-matched control subjects. ICD symptoms were identified using the South Oaks Gambling Screen and modified Minnesota Impulse Disorders Interview. Results: A higher prevalence of pathological gambling and hypersexuality was found in PD patients than in control subjects. A higher frequency of pathological gambling in our sample of young-onset PD patients was found in patients using dopamine agonists and in patients with dyskinesias lasting 5 or more years. The frequency of any ICD symptom was associated with coffee consumption, higher reported anxiety, and somatization. ICD symptoms were also related to personality characteristics in PD patients; specifically, patients who manifested any ICD symptom scored significantly higher on Self-assertive/ Antisocial and Reserved/Schizoid personality styles and pathological gambling was associated with lower reported Conscientiousness. Conclusion: Our results demonstrate that ICD presents a real problem in young-onset PD patients. Knowledge about the factors associated with ICD symptoms might be helpful in the proactive search for these pathological behaviours in this specific subgroup of PD patients.
Links
NV15-30062A, research and development projectName: Fenotypy impulzivity u neuropsychiatrických poruch a jejich klinický význam
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