MENG, Geng, Xinzheng ZHANG, Pavel PLEVKA, Qian YU, Peter TIJSSEN and Michael G. ROSSMANN. The Structure and Host Entry of an Invertebrate Parvovirus. JOURNAL OF VIROLOGY. WASHINGTON: AMER SOC MICROBIOLOGY, 2013, vol. 87, No 23, p. 12523-12530. ISSN 0022-538X. Available from: https://dx.doi.org/10.1128/JVI.01822-13. |
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@article{1376794, author = {Meng, Geng and Zhang, Xinzheng and Plevka, Pavel and Yu, Qian and Tijssen, Peter and Rossmann, Michael G.}, article_location = {WASHINGTON}, article_number = {23}, doi = {http://dx.doi.org/10.1128/JVI.01822-13}, language = {eng}, issn = {0022-538X}, journal = {JOURNAL OF VIROLOGY}, title = {The Structure and Host Entry of an Invertebrate Parvovirus}, volume = {87}, year = {2013} }
TY - JOUR ID - 1376794 AU - Meng, Geng - Zhang, Xinzheng - Plevka, Pavel - Yu, Qian - Tijssen, Peter - Rossmann, Michael G. PY - 2013 TI - The Structure and Host Entry of an Invertebrate Parvovirus JF - JOURNAL OF VIROLOGY VL - 87 IS - 23 SP - 12523-12530 EP - 12523-12530 PB - AMER SOC MICROBIOLOGY SN - 0022538X N2 - The 3.5-angstrom resolution X-ray crystal structure of mature cricket parvovirus (Acheta domesticus densovirus [AdDNV]) has been determined. Structural comparisons show that vertebrate and invertebrate parvoviruses have evolved independently, although there are common structural features among all parvovirus capsid proteins. It was shown that raising the temperature of the AdDNV particles caused a loss of their genomes. The structure of these emptied particles was determined by cryo-electron microscopy to 5.5-angstrom resolution, and the capsid structure was found to be the same as that for the full, mature virus except for the absence of the three ordered nucleotides observed in the crystal structure. The viral protein 1 (VP1) amino termini could be externalized without significant damage to the capsid. In vitro, this externalization of the VP1 amino termini is accompanied by the release of the viral genome. ER -
MENG, Geng, Xinzheng ZHANG, Pavel PLEVKA, Qian YU, Peter TIJSSEN and Michael G. ROSSMANN. The Structure and Host Entry of an Invertebrate Parvovirus. \textit{JOURNAL OF VIROLOGY}. WASHINGTON: AMER SOC MICROBIOLOGY, 2013, vol.~87, No~23, p.~12523-12530. ISSN~0022-538X. Available from: https://dx.doi.org/10.1128/JVI.01822-13.
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