PLEVKA, Pavel, Rushika PERERA, Jane CARDOSA, Richard J. KUHN and Michael G. ROSSMANN. Structure determination of enterovirus 71. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. HOBOKEN: WILEY-BLACKWELL, 2012, vol. 68, September, p. 1217-1222. ISSN 0907-4449. Available from: https://dx.doi.org/10.1107/S0907444912025772.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Structure determination of enterovirus 71
Authors PLEVKA, Pavel, Rushika PERERA, Jane CARDOSA, Richard J. KUHN and Michael G. ROSSMANN.
Edition ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, HOBOKEN, WILEY-BLACKWELL, 2012, 0907-4449.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10600 1.6 Biological sciences
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 14.103
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1107/S0907444912025772
UT WoS 000308330000017
Keywords in English COMMON COLD VIRUS; DECAY-ACCELERATING FACTOR; HUMAN RHINOVIRUS-14; COXSACKIEVIRUS B3; POLIOVIRUS; CRYSTALLOGRAPHY; PICORNAVIRUS; RESOLUTION; SOFTWARE; MALAYSIA
Tags neMU
Changed by Changed by: Mgr. Eva Špillingová, učo 110713. Changed: 29/3/2017 14:31.
Abstract
Enterovirus 71 is a picornavirus that causes hand, foot and mouth disease but may induce fatal neurological illness in infants and young children. Enterovirus 71 crystallized in a body-centered orthorhombic space group with two particles in general orientations in the crystallographic asymmetric unit. Determination of the particle orientations required that the locked rotation function excluded the twofold symmetry axes from the set of icosahedral symmetry operators. This avoided the occurrence of misleading high rotation-function values produced by the alignment of icosahedral and crystallographic twofold axes. Once the orientations and positions of the particles had been established, the structure was solved by molecular replacement and phase extension.
PrintDisplayed: 28/7/2024 18:28