R 2017

pqsfinder: identification of potential quadruplex forming sequences

HON, Jiří, Matej LEXA, Tomáš MARTÍNEK and Jaroslav ZENDULKA

Basic information

Original name

pqsfinder: identification of potential quadruplex forming sequences

Name in Czech

pqsfinder: R/Bioconductor balíček pro identifikaci sekvencí tvořících kvadruplexy

Authors

HON, Jiří (203 Czech Republic), Matej LEXA (703 Slovakia, belonging to the institution), Tomáš MARTÍNEK (203 Czech Republic) and Jaroslav ZENDULKA (203 Czech Republic)

Edition

2017

Other information

Language

English

Type of outcome

Software

Field of Study

10201 Computer sciences, information science, bioinformatics

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14330/17:00094706

Organization unit

Faculty of Informatics

DOI

Keywords (in Czech)

G-kvadruplex; kvadruplex; DNA; R; Bioconductor; rozpoznávání vzorů; vyhledávání; anotace

Keywords in English

G-quadruplex; quadruplex; DNA; R; Bioconductor; pattern matching; searching; annotation

Technical parameters

Součást prostředí R-Bioconductor

Tags

International impact, Reviewed
Změněno: 6/11/2017 22:43, doc. Ing. Matej Lexa, Ph.D.

Abstract

V originále

The main functionality of the this package is to detect DNA sequence patterns that are likely to fold into an intramolecular G-quadruplex (G4). Unlike many other approaches, this package is able to detect sequences responsible for G4s folded from imperfect G-runs containing bulges or mismatches and as such is more sensitive than competing algorithms.

Links

GA15-02891S, research and development project
Name: Rostlinné transpozony a konformace DNA
Investor: Czech Science Foundation