HON, Jiří, Matej LEXA, Tomáš MARTÍNEK and Jaroslav ZENDULKA. pqsfinder: identification of potential quadruplex forming sequences. 2017. Available from: https://dx.doi.org/10.18129/B9.bioc.pqsfinder.
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Basic information
Original name pqsfinder: identification of potential quadruplex forming sequences
Name in Czech pqsfinder: R/Bioconductor balíček pro identifikaci sekvencí tvořících kvadruplexy
Authors HON, Jiří (203 Czech Republic), Matej LEXA (703 Slovakia, belonging to the institution), Tomáš MARTÍNEK (203 Czech Republic) and Jaroslav ZENDULKA (203 Czech Republic).
Edition 2017.
Other information
Original language English
Type of outcome Software
Field of Study 10201 Computer sciences, information science, bioinformatics
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW pqsfinder: Identification of potential quadruplex forming sequences
RIV identification code RIV/00216224:14330/17:00094706
Organization unit Faculty of Informatics
Doi http://dx.doi.org/10.18129/B9.bioc.pqsfinder
Keywords (in Czech) G-kvadruplex; kvadruplex; DNA; R; Bioconductor; rozpoznávání vzorů; vyhledávání; anotace
Keywords in English G-quadruplex; quadruplex; DNA; R; Bioconductor; pattern matching; searching; annotation
Technical parameters Součást prostředí R-Bioconductor
Tags International impact, Reviewed
Changed by Changed by: doc. Ing. Matej Lexa, Ph.D., učo 31298. Changed: 6/11/2017 22:43.
Abstract
The main functionality of the this package is to detect DNA sequence patterns that are likely to fold into an intramolecular G-quadruplex (G4). Unlike many other approaches, this package is able to detect sequences responsible for G4s folded from imperfect G-runs containing bulges or mismatches and as such is more sensitive than competing algorithms.
Links
GA15-02891S, research and development projectName: Rostlinné transpozony a konformace DNA
Investor: Czech Science Foundation
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