Detailed Information on Publication Record
2018
Differences in food intake and genetic variability in taste receptors between Czech pregnant women with and without gestational diabetes mellitus
BARTÁKOVÁ, Vendula, Katarína CHALÁSOVÁ, Filip ZLÁMAL, Jana BĚLOBRÁDKOVÁ, Kateřina KAŇKOVÁ et. al.Basic information
Original name
Differences in food intake and genetic variability in taste receptors between Czech pregnant women with and without gestational diabetes mellitus
Authors
BARTÁKOVÁ, Vendula (203 Czech Republic, guarantor, belonging to the institution), Katarína CHALÁSOVÁ (703 Slovakia, belonging to the institution), Filip ZLÁMAL (203 Czech Republic, belonging to the institution), Jana BĚLOBRÁDKOVÁ (203 Czech Republic) and Kateřina KAŇKOVÁ (203 Czech Republic, belonging to the institution)
Edition
European Journal of Nutrition, Heidelberg, Springer, 2018, 1436-6207
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30308 Nutrition, Dietetics
Country of publisher
Germany
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 4.449
RIV identification code
RIV/00216224:14110/18:00106903
Organization unit
Faculty of Medicine
UT WoS
000427285000009
Keywords in English
Dietary intake; Food preferences; Genetic variability; Gestational diabetes mellitus; Single nucleotide polymorphism; Taste receptors
Tags
International impact, Reviewed
Změněno: 2/5/2019 13:02, Soňa Böhmová
Abstract
V originále
Purpose: Gestational diabetes mellitus (GDM) represents the most frequent metabolic disorder in pregnancy. Since dietary intake plays an important role in obesity and type 2 diabetes development, it is likely to be for the susceptibility to GDM too. Food preferences, driving partly the diet composition, are changing during pregnancy. Taste and genetic variability in taste receptors is an important factor in determining food preferences. Aims of our study were (1) to characterize dietary habits of pregnant women and to find possible differences in food preferences between healthy pregnant women and those with GDM and (2) to ascertain possible association of several single nucleotide polymorphisms (SNPs) in taste receptor (TR) genes with GDM. Methods: A total of 363 pregnant women (293 with GDM and 70 with physiologic pregnancy) were included in the study. Dietary pattern spanning the period of approx. 6 months preceding the time of GDM screening was assessed using a semi-quantitative food frequency questionnaire. A total of five SNPs in TR genes were selected for genotyping based on their functionality or previous associations. Results: Women with GDM exhibited significantly more frequent meat consumption (esp. poultry, pork and smoked meat), dairy products and sweet beverages consumption. The legumes consumption was found to be inversely correlated with fasting glycaemia (P = 0.007, Spearman). CC genotype in TAS2R9 gene (SNP rs3741845) was significantly associated with GDM (P = 0.0087, Chi-square test). Conclusions: Our study showed differences in dietary intake of selected food items between healthy pregnant women and those with GDM and genetic association of bitter taste receptor allele with GDM.
Links
| NV16-28040A, research and development project |
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