BENEJ, Michal, Ivan ČAPOV, Jana SKŘIČKOVÁ, Karel HEJDUK, Adam PEŠTÁL, Jan WECHSLER, H. ČOUPKOVÁ and V. HYTYCH. Association of the postoperative white blood cells (WBC) count in peripheral blood after radical surgical treatment of left upper lobe non-small cell lung cancer (NSCLC) with overall survival - single center results. Bratislava Medical Journal - Bratislavské lekárske listy. Bratislava: Univerzita Komenského, 2017, vol. 118, No 5, p. 299-301. ISSN 0006-9248. Available from: https://dx.doi.org/10.4149/BLL_2017_073.
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Basic information
Original name Association of the postoperative white blood cells (WBC) count in peripheral blood after radical surgical treatment of left upper lobe non-small cell lung cancer (NSCLC) with overall survival - single center results
Authors BENEJ, Michal (703 Slovakia, guarantor), Ivan ČAPOV (203 Czech Republic), Jana SKŘIČKOVÁ (203 Czech Republic), Karel HEJDUK (203 Czech Republic, belonging to the institution), Adam PEŠTÁL (203 Czech Republic), Jan WECHSLER (203 Czech Republic), H. ČOUPKOVÁ (203 Czech Republic) and V. HYTYCH (203 Czech Republic).
Edition Bratislava Medical Journal - Bratislavské lekárske listy, Bratislava, Univerzita Komenského, 2017, 0006-9248.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30218 General and internal medicine
Country of publisher Slovakia
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.678
RIV identification code RIV/00216224:14110/17:00097053
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.4149/BLL_2017_073
UT WoS 000403031700010
Keywords in English postoperative white blood cells; peripheral blood; radical surgical treatment; left upper lobe; non-small cell lung cancer; survival-single center results
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 17/5/2018 16:18.
Abstract
INTRODUCTION: The individual patient prognosis after radical surgery for Non-small cell lung cancer (NSCLC) of left upper lobe remains still unclear. The purpose of this study is to evaluate the predictive value of elevated white blood cell count in peripheral blood as early indicator of postoperative NSCLC prognosis. METHODS: A retrospective statistical analysis was performed studying patients subject to radical treatment of left upper lobe NSCLC in period of five years with subsequent one to three-year monitoring of morbidity and mortality of the patient population. The statistical ROC (Receiver Operating Characteristic) analysis of the WBC count in peripheral blood third day after the operation was used to evaluate the relationship with overall survival, with respect to patients surviving for at least 24 months. RESULTS: Based on the results of the ROC analysis with a total area under the curve (AUC) of 0.67, it is possible to confirm that the WBC count established third day after the operation allows us to classify patients into groups according to the 24-month overall survival. CONCLUSION: Our findings confirm the potential of using WBC count to improve current protocols to establish postoperative prognosis for NSCLC of the upper left lobe (Tab. 2, Fig. 1, Ref. 11). Text in PDF www.elis.sk.
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