Nanoparticle-Based Immunochemical Biosensors and Assays: Recent
Advances and Challenges

J 2017

Nanoparticle-Based Immunochemical Biosensors and Assays: Recent Advances and Challenges

FARKA, Zdeněk, Tomáš JUŘÍK, David KOVÁŘ, Libuše TRNKOVÁ, Petr SKLÁDAL et. al.

Basic information

Original name

Nanoparticle-Based Immunochemical Biosensors and Assays: Recent Advances and Challenges

Authors

FARKA, Zdeněk (203 Czech Republic, belonging to the institution), Tomáš JUŘÍK (203 Czech Republic, belonging to the institution), David KOVÁŘ (203 Czech Republic, belonging to the institution), Libuše TRNKOVÁ (203 Czech Republic, belonging to the institution) and Petr SKLÁDAL (203 Czech Republic, guarantor, belonging to the institution)

Edition

Chemical Reviews, Washington, D.C., USA, American Chemical Society, 2017, 0009-2665

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10406 Analytical chemistry

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 52.613

RIV identification code

RIV/00216224:14740/17:00097309

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1021/acs.chemrev.7b00037

UT WoS

000407540500004

Keywords in English

Immunosensor; Immunoassay; Nanoparticle; Antibody

Abstract

V originále

We review the progress achieved during the recent five years in immunochemical biosensors (immunosensors) combined with nanoparticles for enhanced sensitivity. The initial part introduces antibodies as classic recognition elements. The optical sensing part describes fluorescent, luminescent, and surface plasmon resonance systems. Amperometry, voltammetry, and impedance spectroscopy represent electrochemical transducer methods; electrochemiluminescence with photoelectric conversion constitutes a widely utilized combined method. The transducing options function together with suitable nanoparticles: metallic and metal oxides, including magnetic ones, carbon-based nanotubes, graphene variants, luminescent carbon dots, nanocrystals as quantum dots, and photon up-converting particles. These sources merged together provide extreme variability of existing nanoimmunosensing options. Finally, applications in clinical analysis (markers, tumor cells, and pharmaceuticals) and in the detection of pathogenic microorganisms, toxic agents, and pesticides in the environmental field and food products are summarized.

Links

LQ1601, research and development project

Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

FARKA, Zdeněk, Tomáš JUŘÍK, David KOVÁŘ, Libuše TRNKOVÁ and Petr SKLÁDAL. Nanoparticle-Based Immunochemical Biosensors and Assays: Recent Advances and Challenges. Chemical Reviews. Washington, D.C., USA: American Chemical Society, 2017, vol. 117, No 15, p. 9973-10042. ISSN 0009-2665. Available from: https://dx.doi.org/10.1021/acs.chemrev.7b00037.

@article{1386732,
   author = {Farka, Zdeněk and Juřík, Tomáš and Kovář, David and Trnková, Libuše and Skládal, Petr},
   article_location = {Washington, D.C., USA},
   article_number = {15},
   doi = {http://dx.doi.org/10.1021/acs.chemrev.7b00037},
   keywords = {Immunosensor; Immunoassay; Nanoparticle; Antibody},
   language = {eng},
   issn = {0009-2665},
   journal = {Chemical Reviews},
   title = {Nanoparticle-Based Immunochemical Biosensors and Assays: Recent Advances and Challenges},
   url = {http://pubs.acs.org/doi/abs/10.1021/acs.chemrev.7b00037},
   volume = {117},
   year = {2017}
}

TY  - JOUR
ID  - 1386732
AU  - Farka, Zdeněk - Juřík, Tomáš - Kovář, David - Trnková, Libuše - Skládal, Petr
PY  - 2017
TI  - Nanoparticle-Based Immunochemical Biosensors and Assays: Recent Advances and Challenges
JF  - Chemical Reviews
VL  - 117
IS  - 15
SP  - 9973-10042
EP  - 9973-10042
PB  - American Chemical Society
SN  - 00092665
KW  - Immunosensor
KW  - Immunoassay
KW  - Nanoparticle
KW  - Antibody
UR  - http://pubs.acs.org/doi/abs/10.1021/acs.chemrev.7b00037
L2  - http://pubs.acs.org/doi/abs/10.1021/acs.chemrev.7b00037
N2  - We review the progress achieved during the recent five years in immunochemical biosensors (immunosensors) combined with nanoparticles for enhanced sensitivity. The initial part introduces antibodies as classic recognition elements. The optical sensing part describes fluorescent, luminescent, and surface plasmon resonance systems. Amperometry, voltammetry, and impedance spectroscopy represent electrochemical transducer methods; electrochemiluminescence with photoelectric conversion constitutes a widely utilized combined method. The transducing options function together with suitable nanoparticles: metallic and metal oxides, including magnetic ones, carbon-based nanotubes, graphene variants, luminescent carbon dots, nanocrystals as quantum dots, and photon up-converting particles. These sources merged together provide extreme variability of existing nanoimmunosensing options. Finally, applications in clinical analysis (markers, tumor cells, and pharmaceuticals) and in the detection of pathogenic microorganisms, toxic agents, and pesticides in the environmental field and food products are summarized.
ER  -

FARKA, Zdeněk, Tomáš JUŘÍK, David KOVÁŘ, Libuše TRNKOVÁ and Petr SKLÁDAL. Nanoparticle-Based Immunochemical Biosensors and Assays: Recent Advances and Challenges. \textit{Chemical Reviews}. Washington, D.C., USA: American Chemical Society, 2017, vol.~117, No~15, p.~9973-10042. ISSN~0009-2665. Available from: https://dx.doi.org/10.1021/acs.chemrev.7b00037.

Detailed Information on Publication Record