FARKA, Zdeněk, Tomáš JUŘÍK, David KOVÁŘ, Libuše TRNKOVÁ and Petr SKLÁDAL. Nanoparticle-Based Immunochemical Biosensors and Assays: Recent Advances and Challenges. Chemical Reviews. Washington, D.C., USA: American Chemical Society, 2017, vol. 117, No 15, p. 9973-10042. ISSN 0009-2665. Available from: https://dx.doi.org/10.1021/acs.chemrev.7b00037.
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Basic information
Original name Nanoparticle-Based Immunochemical Biosensors and Assays: Recent Advances and Challenges
Authors FARKA, Zdeněk (203 Czech Republic, belonging to the institution), Tomáš JUŘÍK (203 Czech Republic, belonging to the institution), David KOVÁŘ (203 Czech Republic, belonging to the institution), Libuše TRNKOVÁ (203 Czech Republic, belonging to the institution) and Petr SKLÁDAL (203 Czech Republic, guarantor, belonging to the institution).
Edition Chemical Reviews, Washington, D.C., USA, American Chemical Society, 2017, 0009-2665.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10406 Analytical chemistry
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 52.613
RIV identification code RIV/00216224:14740/17:00097309
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1021/acs.chemrev.7b00037
UT WoS 000407540500004
Keywords in English Immunosensor; Immunoassay; Nanoparticle; Antibody
Tags rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Marie Šípková, DiS., učo 437722. Changed: 23/4/2020 17:29.
We review the progress achieved during the recent five years in immunochemical biosensors (immunosensors) combined with nanoparticles for enhanced sensitivity. The initial part introduces antibodies as classic recognition elements. The optical sensing part describes fluorescent, luminescent, and surface plasmon resonance systems. Amperometry, voltammetry, and impedance spectroscopy represent electrochemical transducer methods; electrochemiluminescence with photoelectric conversion constitutes a widely utilized combined method. The transducing options function together with suitable nanoparticles: metallic and metal oxides, including magnetic ones, carbon-based nanotubes, graphene variants, luminescent carbon dots, nanocrystals as quantum dots, and photon up-converting particles. These sources merged together provide extreme variability of existing nanoimmunosensing options. Finally, applications in clinical analysis (markers, tumor cells, and pharmaceuticals) and in the detection of pathogenic microorganisms, toxic agents, and pesticides in the environmental field and food products are summarized.
LQ1601, research and development projectName: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR
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