| KOTÁSKOVÁ, Iva, Petr NĚMEC, Martina VANĚRKOVÁ, Barbora MALIŠOVÁ, Renata TEJKALOVÁ, Marek ORBAN, Víta ŽAMPACHOVÁ and Tomáš FREIBERGER. First report of Sneathia sanguinegens together with Mycoplasma hominis in postpartum prosthetic valve infective endocarditis: a case report. BMC INFECTIOUS DISEASES. London: BIOMED CENTRAL LTD, 2017, vol. 17, August, p. nestránkováno, 7 pp. ISSN 1471-2334. Available from: https://dx.doi.org/10.1186/s12879-017-2654-8. |
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@article{1387305,
author = {Kotásková, Iva and Němec, Petr and Vaněrková, Martina and Mališová, Barbora and Tejkalová, Renata and Orban, Marek and Žampachová, Víta and Freiberger, Tomáš},
article_location = {London},
article_number = {August},
doi = {http://dx.doi.org/10.1186/s12879-017-2654-8},
keywords = {Infective endocarditis; Postpartum endocarditis; Sneathia; Mycoplasma; Polymicrobial infections},
language = {eng},
issn = {1471-2334},
journal = {BMC INFECTIOUS DISEASES},
title = {First report of Sneathia sanguinegens together with Mycoplasma hominis in postpartum prosthetic valve infective endocarditis: a case report},
url = {https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-017-2654-8},
volume = {17},
year = {2017}
}
TY - JOUR
ID - 1387305
AU - Kotásková, Iva - Němec, Petr - Vaněrková, Martina - Mališová, Barbora - Tejkalová, Renata - Orban, Marek - Žampachová, Víta - Freiberger, Tomáš
PY - 2017
TI - First report of Sneathia sanguinegens together with Mycoplasma hominis in postpartum prosthetic valve infective endocarditis: a case report
JF - BMC INFECTIOUS DISEASES
VL - 17
IS - August
SP - nestránkováno
EP - nestránkováno
PB - BIOMED CENTRAL LTD
SN - 14712334
KW - Infective endocarditis
KW - Postpartum endocarditis
KW - Sneathia
KW - Mycoplasma
KW - Polymicrobial infections
UR - https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-017-2654-8
L2 - https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-017-2654-8
N2 - Background: The presence of more than one bacterial agent is relatively rare in infective endocarditis, although more common in prosthetic cases. Molecular diagnosis from a removed heart tissue is considered a quick and effective way to diagnose fastidious or intracellular agents. Case presentation: Here we describe the case of postpartum polymicrobial prosthetic valve endocarditis in a young woman. Sneathia sanguinegens and Mycoplasma hominis were simultaneously detected from the heart valve sample using broad range 16S rRNA polymerase chain reaction (PCR) followed by sequencing while culture remained negative. Results were confirmed by independent PCR combined with denaturing gradient gel electrophoresis. Before the final agent identification, the highly non-compliant patient left from the hospital against medical advice on empirical intravenous treatment with aminopenicillins, clavulanate and gentamicin switched to oral amoxycillin and clavulanate. Four months after surgery, no signs of inflammation were present despite new regurgitation and valve leaflet flail was detected. However, after another 5 months the patient died from sepsis and recurrent infective endocarditis of unclarified etiology. Conclusions: Mycoplasma hominis is a rare causative agent of infective endocarditis. To the best of our knowledge, presented case is the first report of Sneathia sanguinegens detected in this condition. Molecular techniques were shown to be useful even in polymicrobial infective endocarditis samples.
ER -
KOTÁSKOVÁ, Iva, Petr NĚMEC, Martina VANĚRKOVÁ, Barbora MALIŠOVÁ, Renata TEJKALOVÁ, Marek ORBAN, Víta ŽAMPACHOVÁ and Tomáš FREIBERGER. First report of Sneathia sanguinegens together with Mycoplasma hominis in postpartum prosthetic valve infective endocarditis: a case report. \textit{BMC INFECTIOUS DISEASES}. London: BIOMED CENTRAL LTD, 2017, vol.~17, August, p.~nestránkováno, 7 pp. ISSN~1471-2334. Available from: https://dx.doi.org/10.1186/s12879-017-2654-8.
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