BORYS, Sylwia, Ronza KHOZMI, Wieslawa KRANS, Artur BRYJA, Marta DYSZKIEWICZ-KONWIŃSKA, Michal JEŠETA and Bartosz KEMPISTY. Recent Findings of the Types of Programmed Cell Death. Advances in Cell Biology. Warsaw: Polskie towarzystwo anatomiczne, 2017, vol. 5, No 1, p. 43-49. ISSN 0324-833X. Available from: https://dx.doi.org/10.1515/acb-2017-0004.
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Basic information
Original name Recent Findings of the Types of Programmed Cell Death
Authors BORYS, Sylwia (616 Poland), Ronza KHOZMI (616 Poland), Wieslawa KRANS (616 Poland), Artur BRYJA (616 Poland), Marta DYSZKIEWICZ-KONWIŃSKA (616 Poland), Michal JEŠETA (203 Czech Republic, guarantor, belonging to the institution) and Bartosz KEMPISTY (616 Poland).
Edition Advances in Cell Biology, Warsaw, Polskie towarzystwo anatomiczne, 2017, 0324-833X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30214 Obstetrics and gynaecology
Country of publisher Poland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.147
RIV identification code RIV/00216224:14110/17:00097424
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1515/acb-2017-0004
Keywords in English apoptosis; mitochondrial apoptosis pathway; necrosis; receptor-dependent apotposis; pathway
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 20/3/2018 16:29.
Abstract
Cell death plays an important role in maintaining the homeostasis of multicellular organisms. It can occur in a controlled manner by apoptosis or autophagy. Cell death which occurs regardless of regulatory factors include necrosis, mitotic catastrophe or oncosis. Apoptosis and necrosis are cellular process that leads to cell death. However their mechanisms are different, although factors triggering them can be similar. Necrosis and apoptosis have many different characteristics in terms of biochemistry and morphology. There are two main pathways of apoptosis induction signal: Receptor - dependent and mitochondrial. The outsider apoptotic pathway is induced by external factors stimulating membrane receptors having an intracellular domain called death domain. Mitochondrial apoptotic pathway is activated by increased concentration of reactive oxygen species (ROS), DNA damage, disorders electrolyte transport and an increase in the concentration of the calcium ions in the cytoplasm. In response to stress-factors, mitochondrial channels are opened, so that is released into the cytoplasm cytochrome C. This work is aimed at an overall description of exchanged processes.
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