ONDRUŠOVÁ, Katarína, Jana SVAČINOVÁ, Michal JAVORKA, Jan NOVÁK, Marie NOVÁKOVÁ and Zuzana NOVÁKOVÁ. Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury. Journal of Neurotrauma. New York: Mary Ann Liebert, vol. 34, No 24, p. 3381-3387. ISSN 0897-7151. doi:10.1089/neu.2017.4989. 2017.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury
Authors ONDRUŠOVÁ, Katarína (703 Slovakia, belonging to the institution), Jana SVAČINOVÁ (203 Czech Republic, belonging to the institution), Michal JAVORKA (703 Slovakia), Jan NOVÁK (203 Czech Republic, belonging to the institution), Marie NOVÁKOVÁ (203 Czech Republic, belonging to the institution) and Zuzana NOVÁKOVÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition Journal of Neurotrauma, New York, Mary Ann Liebert, 2017, 0897-7151.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30218 General and internal medicine
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 5.002
RIV identification code RIV/00216224:14110/17:00097487
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1089/neu.2017.4989
UT WoS 000417633700007
Keywords (in Czech) Citlivost baroreflexu; poranění míchy; ortostáza; kauzální analýza
Keywords in English Baroreflex sensitivity; spinal cord injury; orthostasis; causal analysis
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 20/3/2018 16:31.
Abstract
The level of spinal cord injury affects baroreflex regulation of blood pressure. While a parasympathetic cardiac chronotropic effect is preserved, baroreflex response could be impaired by sympathetic dysfunction under the SCI level. This study was aimed to evaluate the baroreflex function in spinal cord injury patients by the analysis of causal interaction between systolic blood pressure and inter-beat intervals. Baroreflex dysfunction in spinal cord injury patients was detected using causal analysis methods during orthostatic challenge only. Baroreflex dysfunction is probably an important mechanism of the more expressed blood pressure decrease associated with cervical spinal cord injury. The severity of autonomic dysfunction was related to spinal cord injury level.
Links
MUNI/A/1355/2016, interní kód MUName: Kardiovaskulární systém očima molekulární fyziologie
Investor: Masaryk University, Category A
PrintDisplayed: 20/4/2024 01:24