Impaired baroreflex function during orthostatic challenge in
patients after spinal cord injury

J 2017

Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury

ONDRUŠOVÁ, Katarína, Jana SVAČINOVÁ, Michal JAVORKA, Jan NOVÁK, Marie NOVÁKOVÁ et. al.

Basic information

Original name

Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury

Authors

ONDRUŠOVÁ, Katarína (703 Slovakia, belonging to the institution), Jana SVAČINOVÁ (203 Czech Republic, belonging to the institution), Michal JAVORKA (703 Slovakia), Jan NOVÁK (203 Czech Republic, belonging to the institution), Marie NOVÁKOVÁ (203 Czech Republic, belonging to the institution) and Zuzana NOVÁKOVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Journal of Neurotrauma, New York, Mary Ann Liebert, 2017, 0897-7151

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30218 General and internal medicine

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 5.002

RIV identification code

RIV/00216224:14110/17:00097487

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1089/neu.2017.4989

UT WoS

000417633700007

Keywords (in Czech)

Citlivost baroreflexu; poranění míchy; ortostáza; kauzální analýza

Keywords in English

Baroreflex sensitivity; spinal cord injury; orthostasis; causal analysis

Abstract

V originále

The level of spinal cord injury affects baroreflex regulation of blood pressure. While a parasympathetic cardiac chronotropic effect is preserved, baroreflex response could be impaired by sympathetic dysfunction under the SCI level. This study was aimed to evaluate the baroreflex function in spinal cord injury patients by the analysis of causal interaction between systolic blood pressure and inter-beat intervals. Baroreflex dysfunction in spinal cord injury patients was detected using causal analysis methods during orthostatic challenge only. Baroreflex dysfunction is probably an important mechanism of the more expressed blood pressure decrease associated with cervical spinal cord injury. The severity of autonomic dysfunction was related to spinal cord injury level.

Links

MUNI/A/1355/2016, interní kód MU

Name: Kardiovaskulární systém očima molekulární fyziologie

Investor: Masaryk University, Category A

Citovat

ONDRUŠOVÁ, Katarína, Jana SVAČINOVÁ, Michal JAVORKA, Jan NOVÁK, Marie NOVÁKOVÁ and Zuzana NOVÁKOVÁ. Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury. Journal of Neurotrauma. New York: Mary Ann Liebert, 2017, vol. 34, No 24, p. 3381-3387. ISSN 0897-7151. Available from: https://dx.doi.org/10.1089/neu.2017.4989.

@article{1388731,
   author = {Ondrušová, Katarína and Svačinová, Jana and Javorka, Michal and Novák, Jan and Nováková, Marie and Nováková, Zuzana},
   article_location = {New York},
   article_number = {24},
   doi = {http://dx.doi.org/10.1089/neu.2017.4989},
   keywords = {Baroreflex sensitivity; spinal cord injury; orthostasis; causal analysis},
   language = {eng},
   issn = {0897-7151},
   journal = {Journal of Neurotrauma},
   title = {Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury},
   volume = {34},
   year = {2017}
}

TY  - JOUR
ID  - 1388731
AU  - Ondrušová, Katarína - Svačinová, Jana - Javorka, Michal - Novák, Jan - Nováková, Marie - Nováková, Zuzana
PY  - 2017
TI  - Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury
JF  - Journal of Neurotrauma
VL  - 34
IS  - 24
SP  - 3381-3387
EP  - 3381-3387
PB  - Mary Ann Liebert
SN  - 08977151
KW  - Baroreflex sensitivity
KW  - spinal cord injury
KW  - orthostasis
KW  - causal analysis
N2  - The level of spinal cord injury affects baroreflex regulation of blood pressure. While a parasympathetic cardiac chronotropic effect is preserved, baroreflex response could be impaired by sympathetic dysfunction under the SCI level. This study was aimed to evaluate the baroreflex function in spinal cord injury patients by the analysis of causal interaction between systolic blood pressure and inter-beat intervals. Baroreflex dysfunction in spinal cord injury patients was detected using causal analysis methods during orthostatic challenge only. Baroreflex dysfunction is probably an important mechanism of the more expressed blood pressure decrease associated with cervical spinal cord injury. The severity of autonomic dysfunction was related to spinal cord injury level.
ER  -

ONDRUŠOVÁ, Katarína, Jana SVAČINOVÁ, Michal JAVORKA, Jan NOVÁK, Marie NOVÁKOVÁ and Zuzana NOVÁKOVÁ. Impaired baroreflex function during orthostatic challenge in patients after spinal cord injury. \textit{Journal of Neurotrauma}. New York: Mary Ann Liebert, 2017, vol.~34, No~24, p.~3381-3387. ISSN~0897-7151. Available from: https://dx.doi.org/10.1089/neu.2017.4989.

Detailed Information on Publication Record