Cyclopropylamine plasma polymers for increased cell adhesion
and growth

J 2017

Cyclopropylamine plasma polymers for increased cell adhesion and growth

MANAKHOV, Anton, Marie LANDOVÁ, Jiřina MEDALOVÁ, Miroslav MICHLÍČEK, Josef POLCAK et. al.

Basic information

Original name

Cyclopropylamine plasma polymers for increased cell adhesion and growth

Authors

MANAKHOV, Anton (643 Russian Federation, belonging to the institution), Marie LANDOVÁ (203 Czech Republic, belonging to the institution), Jiřina MEDALOVÁ (203 Czech Republic, belonging to the institution), Miroslav MICHLÍČEK (203 Czech Republic, belonging to the institution), Josef POLCAK (203 Czech Republic), David NEČAS (203 Czech Republic, belonging to the institution) and Lenka ZAJÍČKOVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Plasma processes and polymers, Weinheim, Wiley-VCH, 2017, 1612-8850

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10305 Fluids and plasma physics

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.700

RIV identification code

RIV/00216224:14740/17:00097542

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1002/ppap.201600123

UT WoS

000405739600004

Keywords in English

amine coatings; cell adhesion; cyclopropylamine; ESCA/XPS; pulsed discharges

Abstract

V originále

Plasma polymers with NHx groups were deposited from cyclopropylamine in low pressure radio frequency (RF) discharges. The amount of NHx decreased with increasing average power P-av, whereas the layer dissolution in water decreased and high P-av led to a slight film swelling. The C2C12 cells demonstrated very high adhesion to the layers regardless of the deposition conditions. Although the surface chemistry of amine-rich layers should enhance the cell proliferation, the WST-1 assay, and immunocytochemistry revealed lower cell proliferation and viability on the layers exhibiting above 18% of relative thickness loss in water. Promising results were obtained on the layers with better water stability and bearing 7-10% of NHx.

Links

LD15150, research and development project

Name: Elektrostaticky zvlákněná biodegradabilní nanovlákna pokrytá plazmově připravenými aminovými vrstvami pro využití v biomedicíně

Investor: Ministry of Education, Youth and Sports of the CR

LQ1601, research and development project

Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

MANAKHOV, Anton, Marie LANDOVÁ, Jiřina MEDALOVÁ, Miroslav MICHLÍČEK, Josef POLCAK, David NEČAS and Lenka ZAJÍČKOVÁ. Cyclopropylamine plasma polymers for increased cell adhesion and growth. Plasma processes and polymers. Weinheim: Wiley-VCH, 2017, vol. 14, No 7, p. nestránkováno, 12 pp. ISSN 1612-8850. Available from: https://dx.doi.org/10.1002/ppap.201600123.

@article{1389320,
   author = {Manakhov, Anton and Landová, Marie and Medalová, Jiřina and Michlíček, Miroslav and Polcak, Josef and Nečas, David and Zajíčková, Lenka},
   article_location = {Weinheim},
   article_number = {7},
   doi = {http://dx.doi.org/10.1002/ppap.201600123},
   keywords = {amine coatings; cell adhesion; cyclopropylamine; ESCA/XPS; pulsed discharges},
   language = {eng},
   issn = {1612-8850},
   journal = {Plasma processes and polymers},
   title = {Cyclopropylamine plasma polymers for increased cell adhesion and growth},
   url = {http://onlinelibrary.wiley.com/doi/10.1002/ppap.201600123/abstract;jsessionid=F73F366060DF262E0A74149729358262.f03t01},
   volume = {14},
   year = {2017}
}

TY  - JOUR
ID  - 1389320
AU  - Manakhov, Anton - Landová, Marie - Medalová, Jiřina - Michlíček, Miroslav - Polcak, Josef - Nečas, David - Zajíčková, Lenka
PY  - 2017
TI  - Cyclopropylamine plasma polymers for increased cell adhesion and growth
JF  - Plasma processes and polymers
VL  - 14
IS  - 7
SP  - nestránkováno
EP  - nestránkováno
PB  - Wiley-VCH
SN  - 16128850
KW  - amine coatings
KW  - cell adhesion
KW  - cyclopropylamine
KW  - ESCA/XPS
KW  - pulsed discharges
UR  - http://onlinelibrary.wiley.com/doi/10.1002/ppap.201600123/abstract;jsessionid=F73F366060DF262E0A74149729358262.f03t01
L2  - http://onlinelibrary.wiley.com/doi/10.1002/ppap.201600123/abstract;jsessionid=F73F366060DF262E0A74149729358262.f03t01
N2  - Plasma polymers with NHx groups were deposited from cyclopropylamine in low pressure radio frequency (RF) discharges. The amount of NHx decreased with increasing average power P-av, whereas the layer dissolution in water decreased and high P-av led to a slight film swelling. The C2C12 cells demonstrated very high adhesion to the layers regardless of the deposition conditions. Although the surface chemistry of amine-rich layers should enhance the cell proliferation, the WST-1 assay, and immunocytochemistry revealed lower cell proliferation and viability on the layers exhibiting above 18% of relative thickness loss in water. Promising results were obtained on the layers with better water stability and bearing 7-10% of NHx.
ER  -

MANAKHOV, Anton, Marie LANDOVÁ, Jiřina MEDALOVÁ, Miroslav MICHLÍČEK, Josef POLCAK, David NEČAS and Lenka ZAJÍČKOVÁ. Cyclopropylamine plasma polymers for increased cell adhesion and growth. \textit{Plasma processes and polymers}. Weinheim: Wiley-VCH, 2017, vol.~14, No~7, p.~nestránkováno, 12 pp. ISSN~1612-8850. Available from: https://dx.doi.org/10.1002/ppap.201600123.

Detailed Information on Publication Record