MANAKHOV, Anton, Marie LANDOVÁ, Jiřina MEDALOVÁ, Miroslav MICHLÍČEK, Josef POLCAK, David NEČAS and Lenka ZAJÍČKOVÁ. Cyclopropylamine plasma polymers for increased cell adhesion and growth. Plasma processes and polymers. Weinheim: Wiley-VCH, vol. 14, No 7, p. nestránkováno, 12 pp. ISSN 1612-8850. doi:10.1002/ppap.201600123. 2017.
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Basic information
Original name Cyclopropylamine plasma polymers for increased cell adhesion and growth
Authors MANAKHOV, Anton (643 Russian Federation, belonging to the institution), Marie LANDOVÁ (203 Czech Republic, belonging to the institution), Jiřina MEDALOVÁ (203 Czech Republic, belonging to the institution), Miroslav MICHLÍČEK (203 Czech Republic, belonging to the institution), Josef POLCAK (203 Czech Republic), David NEČAS (203 Czech Republic, belonging to the institution) and Lenka ZAJÍČKOVÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition Plasma processes and polymers, Weinheim, Wiley-VCH, 2017, 1612-8850.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10305 Fluids and plasma physics
Country of publisher Germany
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 2.700
RIV identification code RIV/00216224:14740/17:00097542
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1002/ppap.201600123
UT WoS 000405739600004
Keywords in English amine coatings; cell adhesion; cyclopropylamine; ESCA/XPS; pulsed discharges
Tags rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. David Nečas, Ph.D., učo 19972. Changed: 21/3/2018 10:48.
Abstract
Plasma polymers with NHx groups were deposited from cyclopropylamine in low pressure radio frequency (RF) discharges. The amount of NHx decreased with increasing average power P-av, whereas the layer dissolution in water decreased and high P-av led to a slight film swelling. The C2C12 cells demonstrated very high adhesion to the layers regardless of the deposition conditions. Although the surface chemistry of amine-rich layers should enhance the cell proliferation, the WST-1 assay, and immunocytochemistry revealed lower cell proliferation and viability on the layers exhibiting above 18% of relative thickness loss in water. Promising results were obtained on the layers with better water stability and bearing 7-10% of NHx.
Links
LD15150, research and development projectName: Elektrostaticky zvlákněná biodegradabilní nanovlákna pokrytá plazmově připravenými aminovými vrstvami pro využití v biomedicíně
Investor: Ministry of Education, Youth and Sports of the CR
LQ1601, research and development projectName: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR
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