Prevalence and Predictors of Early Heart Failure With Preserved
Ejection Fraction in Patients With Paroxysmal Atrial
Fibrillation

J 2017

Prevalence and Predictors of Early Heart Failure With Preserved Ejection Fraction in Patients With Paroxysmal Atrial Fibrillation

MELUZÍN, Jaroslav, Zdeněk STÁREK, Tomáš KULÍK, Jiří JEŽ, František LEHAR et. al.

Basic information

Original name

Prevalence and Predictors of Early Heart Failure With Preserved Ejection Fraction in Patients With Paroxysmal Atrial Fibrillation

Authors

MELUZÍN, Jaroslav (203 Czech Republic, guarantor, belonging to the institution), Zdeněk STÁREK (203 Czech Republic, belonging to the institution), Tomáš KULÍK (203 Czech Republic, belonging to the institution), Jiří JEŽ (203 Czech Republic, belonging to the institution), František LEHAR (203 Czech Republic, belonging to the institution), Jiří WOLF (203 Czech Republic, belonging to the institution), Ladislav DUŠEK (203 Czech Republic, belonging to the institution), P. LEINVEBER (203 Czech Republic) and Miroslav NOVÁK (203 Czech Republic, belonging to the institution)

Edition

JOURNAL OF CARDIAC FAILURE, PHILADELPHIA, CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS, 2017, 1071-9164

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 3.942

RIV identification code

RIV/00216224:14110/17:00097556

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.cardfail.2017.04.002

UT WoS

000406733500009

Keywords in English

Left atrial pressure; arm exercise; early heart failure with preserved ejection fraction

Abstract

V originále

Background: Patients with atrial fibrillation (AF) have an increased risk of diastolic dysfunction and heart failure. The purpose of this study was to identify independent predictors. of early (ie, only exercise induced) heart failure with preserved ejection fraction (HFpEF) and to describe the prevalence of early HFpEF among patients with paroxysmal AR. Methods and Results: One hundred patients with paroxysmal AF and preserved left ventricular ejection fraction (LVEF) underwent catheterization for left atrial pressure (LAP) measurements at rest and at the peak of arm exercise (LAP-exe). Based on resting and exercise LAP values, the patients were divided into 3 groups. Sixty-one patients had no evidence of HFpEF (LAP at rest <= 15 mm Hg, LAP-exe <25 mm Hg). Twenty-five subjects had early HFpEF (LAP at rest mm Hg, LAP-exe mm Hg, prevalence 25%). Fourteen patients already had HFpEF at rest (LAP at rest >15 mm Hg). Multivariate exact logistic regression analysis identified age years, LAP at rest mm Hg, and peak systolic mitral annular velocity <= 9.3 cm/s to be independent predictors of early HFpEF. Conclusions: In patients with paroxysmal AF and preserved LVEF, there appears to be a clinically significant prevalence of early HFpEF.

Citovat

MELUZÍN, Jaroslav, Zdeněk STÁREK, Tomáš KULÍK, Jiří JEŽ, František LEHAR, Jiří WOLF, Ladislav DUŠEK, P. LEINVEBER and Miroslav NOVÁK. Prevalence and Predictors of Early Heart Failure With Preserved Ejection Fraction in Patients With Paroxysmal Atrial Fibrillation. JOURNAL OF CARDIAC FAILURE. PHILADELPHIA: CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS, 2017, vol. 23, No 7, p. 558-562. ISSN 1071-9164. Available from: https://dx.doi.org/10.1016/j.cardfail.2017.04.002.

@article{1389399,
   author = {Meluzín, Jaroslav and Stárek, Zdeněk and Kulík, Tomáš and Jež, Jiří and Lehar, František and Wolf, Jiří and Dušek, Ladislav and Leinveber, P. and Novák, Miroslav},
   article_location = {PHILADELPHIA},
   article_number = {7},
   doi = {http://dx.doi.org/10.1016/j.cardfail.2017.04.002},
   keywords = {Left atrial pressure; arm exercise; early heart failure with preserved ejection fraction},
   language = {eng},
   issn = {1071-9164},
   journal = {JOURNAL OF CARDIAC FAILURE},
   title = {Prevalence and Predictors of Early Heart Failure With Preserved Ejection Fraction in Patients With Paroxysmal Atrial Fibrillation},
   volume = {23},
   year = {2017}
}

TY  - JOUR
ID  - 1389399
AU  - Meluzín, Jaroslav - Stárek, Zdeněk - Kulík, Tomáš - Jež, Jiří - Lehar, František - Wolf, Jiří - Dušek, Ladislav - Leinveber, P. - Novák, Miroslav
PY  - 2017
TI  - Prevalence and Predictors of Early Heart Failure With Preserved Ejection Fraction in Patients With Paroxysmal Atrial Fibrillation
JF  - JOURNAL OF CARDIAC FAILURE
VL  - 23
IS  - 7
SP  - 558-562
EP  - 558-562
PB  - CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS
SN  - 10719164
KW  - Left atrial pressure
KW  - arm exercise
KW  - early heart failure with preserved ejection fraction
N2  - Background: Patients with atrial fibrillation (AF) have an increased risk of diastolic dysfunction and heart failure. The purpose of this study was to identify independent predictors. of early (ie, only exercise induced) heart failure with preserved ejection fraction (HFpEF) and to describe the prevalence of early HFpEF among patients with paroxysmal AR. Methods and Results: One hundred patients with paroxysmal AF and preserved left ventricular ejection fraction (LVEF) underwent catheterization for left atrial pressure (LAP) measurements at rest and at the peak of arm exercise (LAP-exe). Based on resting and exercise LAP values, the patients were divided into 3 groups. Sixty-one patients had no evidence of HFpEF (LAP at rest <= 15 mm Hg, LAP-exe <25 mm Hg). Twenty-five subjects had early HFpEF (LAP at rest mm Hg, LAP-exe mm Hg, prevalence 25%). Fourteen patients already had HFpEF at rest (LAP at rest >15 mm Hg). Multivariate exact logistic regression analysis identified age years, LAP at rest mm Hg, and peak systolic mitral annular velocity <= 9.3 cm/s to be independent predictors of early HFpEF. Conclusions: In patients with paroxysmal AF and preserved LVEF, there appears to be a clinically significant prevalence of early HFpEF.
ER  -

MELUZÍN, Jaroslav, Zdeněk STÁREK, Tomáš KULÍK, Jiří JEŽ, František LEHAR, Jiří WOLF, Ladislav DUŠEK, P. LEINVEBER and Miroslav NOVÁK. Prevalence and Predictors of Early Heart Failure With Preserved Ejection Fraction in Patients With Paroxysmal Atrial Fibrillation. \textit{JOURNAL OF CARDIAC FAILURE}. PHILADELPHIA: CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS, 2017, vol.~23, No~7, p.~558-562. ISSN~1071-9164. Available from: https://dx.doi.org/10.1016/j.cardfail.2017.04.002.

Detailed Information on Publication Record