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@article{1390213,
author = {Novak, K. and Polzer, S. and Křivka, Tomáš and Vlachovský, Robert and Staffa, Robert and Kubíček, Luboš and Lambert, L. and Bursa, J.},
article_location = {OXFORD},
article_number = {APR 1 2017},
doi = {http://dx.doi.org/10.1016/j.compbiomed.2017.03.005},
keywords = {Abdominal aortic aneurysm; Correlation analysis; Maximal diameter; Peak wall stress; Peak wall rupture risk},
language = {eng},
issn = {0010-4825},
journal = {Computers in Biology and Medicine},
title = {Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors},
volume = {83},
year = {2017}
}
TY - JOUR
ID - 1390213
AU - Novak, K. - Polzer, S. - Křivka, Tomáš - Vlachovský, Robert - Staffa, Robert - Kubíček, Luboš - Lambert, L. - Bursa, J.
PY - 2017
TI - Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors
JF - Computers in Biology and Medicine
VL - 83
IS - APR 1 2017
SP - 151-156
EP - 151-156
PB - PERGAMON-ELSEVIER SCIENCE LTD
SN - 00104825
KW - Abdominal aortic aneurysm
KW - Correlation analysis
KW - Maximal diameter
KW - Peak wall stress
KW - Peak wall rupture risk
N2 - Purpose: There is no standard for measuring maximal diameter (Dmax) of abdominal aortic aneurysm (AAA) from computer tomography (CT) images although differences between Dmax evaluated from transversal (axialDmax) or orthogonal (orthoDmax) planes can be large especially for angulated AAAs. Therefore we investigated their correlations with alternative rupture risk indicators as peak wall stress (PWS) and peak wall rupture risk (PWRR) to decide which Dmax is more relevant in AAA rupture risk assessment. Material and methods: The Dmax values were measured by a trained radiologist from 70 collected CT scans, and the corresponding PWS and PWRR were evaluated using Finite Element Analysis (FEA). The cohort was ordered according to the difference between axialDmax and orthoDmax (Da-o) quantifying the aneurysm angulation, and Spearman's correlation coefficients between PWS/PWRR orthoDmax/axialDmax were calculated. Results: The calculated correlations PWS/PWRR vs. orthoDmax were substantially higher for angulated AAAs (with Da-o >= 3mm). Under this limit, the correlations were almost the same for both Dmax values. Analysis of AAAs divided into two groups of angulated (n=38) and straight (n=32) cases revealed that both groups are similar in all parameters (orthoDmax, PWS, PWRR) with the exception of axialDmax (p=0.024). Conclusions: It was confirmed that orthoDmax is better correlated with the alternative rupture risk predictors PWS and PWRR for angulated AAA5 (DA-O >= 3mm) while there is no difference between orthoDmax and axialDmax for straight AAAs (DA-O<3mm). As angulated AAA5 represent a significant portion of cases it can be recommended to use orthoDmax as the only Dmax parameter for AAA rupture risk assessment.
ER -
NOVAK, K., S. POLZER, Tomáš KŘIVKA, Robert VLACHOVSKÝ, Robert STAFFA, Luboš KUBÍČEK, L. LAMBERT a J. BURSA. Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors. \textit{Computers in Biology and Medicine}. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, roč.~83, APR 1 2017, s.~151-156. ISSN~0010-4825. doi:10.1016/j.compbiomed.2017.03.005. 2017.
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