NOVAK, K., S. POLZER, Tomáš KŘIVKA, Robert VLACHOVSKÝ, Robert STAFFA, Luboš KUBÍČEK, L. LAMBERT and J. BURSA. Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors. Computers in Biology and Medicine. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2017, vol. 83, APR 1 2017, p. 151-156. ISSN 0010-4825. Available from: https://dx.doi.org/10.1016/j.compbiomed.2017.03.005.
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Basic information
Original name Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors
Authors NOVAK, K. (203 Czech Republic), S. POLZER (203 Czech Republic), Tomáš KŘIVKA (203 Czech Republic, guarantor, belonging to the institution), Robert VLACHOVSKÝ (203 Czech Republic, belonging to the institution), Robert STAFFA (203 Czech Republic, belonging to the institution), Luboš KUBÍČEK (203 Czech Republic, belonging to the institution), L. LAMBERT (203 Czech Republic) and J. BURSA (203 Czech Republic).
Edition Computers in Biology and Medicine, OXFORD, PERGAMON-ELSEVIER SCIENCE LTD, 2017, 0010-4825.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 20601 Medical engineering
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.115
RIV identification code RIV/00216224:14110/17:00097641
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.compbiomed.2017.03.005
UT WoS 000399862200015
Keywords in English Abdominal aortic aneurysm; Correlation analysis; Maximal diameter; Peak wall stress; Peak wall rupture risk
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 18/3/2018 22:31.
Abstract
Purpose: There is no standard for measuring maximal diameter (Dmax) of abdominal aortic aneurysm (AAA) from computer tomography (CT) images although differences between Dmax evaluated from transversal (axialDmax) or orthogonal (orthoDmax) planes can be large especially for angulated AAAs. Therefore we investigated their correlations with alternative rupture risk indicators as peak wall stress (PWS) and peak wall rupture risk (PWRR) to decide which Dmax is more relevant in AAA rupture risk assessment. Material and methods: The Dmax values were measured by a trained radiologist from 70 collected CT scans, and the corresponding PWS and PWRR were evaluated using Finite Element Analysis (FEA). The cohort was ordered according to the difference between axialDmax and orthoDmax (Da-o) quantifying the aneurysm angulation, and Spearman's correlation coefficients between PWS/PWRR orthoDmax/axialDmax were calculated. Results: The calculated correlations PWS/PWRR vs. orthoDmax were substantially higher for angulated AAAs (with Da-o >= 3mm). Under this limit, the correlations were almost the same for both Dmax values. Analysis of AAAs divided into two groups of angulated (n=38) and straight (n=32) cases revealed that both groups are similar in all parameters (orthoDmax, PWS, PWRR) with the exception of axialDmax (p=0.024). Conclusions: It was confirmed that orthoDmax is better correlated with the alternative rupture risk predictors PWS and PWRR for angulated AAA5 (DA-O >= 3mm) while there is no difference between orthoDmax and axialDmax for straight AAAs (DA-O<3mm). As angulated AAA5 represent a significant portion of cases it can be recommended to use orthoDmax as the only Dmax parameter for AAA rupture risk assessment.
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