KUNO, Goro, John S. MACKENZIE, Sandra JUNGLEN, Zdeněk HUBÁLEK, Alexander PLYUSNIN and Duane J. GUBLER. Vertebrate reservoirs of arboviruses: Myth, synonym of amplifier, or reality? VIRUSES-BASEL. BASEL: MDPI AG, 2017, vol. 9, No 7, p. 1-28. ISSN 1999-4915. Available from: https://dx.doi.org/10.3390/v9070185.
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Basic information
Original name Vertebrate reservoirs of arboviruses: Myth, synonym of amplifier, or reality?
Name in Czech Obratlovci jako rezervoár arbovirů: mýtus, synonymum,amplifikátoru nebo realita?
Authors KUNO, Goro, John S. MACKENZIE, Sandra JUNGLEN, Zdeněk HUBÁLEK, Alexander PLYUSNIN and Duane J. GUBLER.
Edition VIRUSES-BASEL, BASEL, MDPI AG, 2017, 1999-4915.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10600 1.6 Biological sciences
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.761
Organization unit Faculty of Science
Doi http://dx.doi.org/10.3390/v9070185
UT WoS 000406684400027
Keywords in English insect-specific virus; arbovirus; transmission mechanism; vertebrate reservoir; origin of arbovirus; virus maintenance; zoonosis; host range
Tags NZ
Tags International impact, Reviewed
Changed by Changed by: Ing. Nicole Zrilić, učo 240776. Changed: 12/4/2018 18:30.
Abstract
The rapid succession of the pandemic of arbovirus diseases, such as dengue, West Nile fever, chikungunya, and Zika fever, has intensified research on these and other arbovirus diseases worldwide. Investigating the unique mode of vector-borne transmission requires a clear understanding of the roles of vertebrates. One major obstacle to this understanding is the ambiguity of the arbovirus definition originally established by the World Health Organization. The paucity of pertinent information on arbovirus transmission at the time contributed to the notion that vertebrates played the role of reservoir in the arbovirus transmission cycle. Because this notion is a salient feature of the arbovirus definition, it is important to reexamine its validity. This review addresses controversial issues concerning vertebrate reservoirs and their role in arbovirus persistence in nature, examines the genesis of the problem from a historical perspective, discusses various unresolved issues from multiple points of view, assesses the present status of the notion in light of current knowledge, and provides options for a solution to resolve the issue.
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