Keeping up with the Red Queen: the pace of aging as an
adaptation

D 2017

Keeping up with the Red Queen: the pace of aging as an adaptation

LENÁRT, Peter and Julie BIENERTOVÁ VAŠKŮ

Basic information

Original name

Keeping up with the Red Queen: the pace of aging as an adaptation

Authors

LENÁRT, Peter (703 Slovakia, guarantor, belonging to the institution) and Julie BIENERTOVÁ VAŠKŮ (203 Czech Republic, belonging to the institution)

Edition

New York, 10th European Congress of Biogerontology combined with the 6th Biogerontological Meeting - The Future of Ageing, p. 693-709, 17 pp. 2017

Publisher

Springer

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

30227 Geriatrics and gerontology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

printed version "print"

Impact factor

Impact factor: 3.702

RIV identification code

RIV/00216224:14110/17:00098201

Organization unit

Faculty of Medicine

ISSN

DOI

http://dx.doi.org/10.1007/s10522-016-9674-4

UT WoS

000405778700022

Keywords in English

Aging; Evolution; Programmed aging; Red Queen; Pace of aging; Aging as an adaptation

Abstract

V originále

For decades, a vast majority of biogerontologists assumed that aging is not and cannot be an adaptation. In recent years, however, several authors opposed this predominant view and repeatedly suggested that not only is aging an adaptation but that it is the result of a specific aging program. This issue almost instantaneously became somewhat controversial and many important authors produced substantial works refuting the notion of the aging program. In this article we review the current state of the debate and list the most important arguments proposed by both sides. Furthermore, although classical interpretations of the evolution of aging are in sharp contrast with the idea of programmed aging, we suggest that the truth might in fact very well lie somewhere in between. We also propose our own interpretation which states that although aging is in essence inevitable and results from damage accumulation rather than from a specific program, the actual rate of aging in nature may still be adaptive to some extent.

Links

EF15_003/0000469, research and development project

Name: Cetocoen Plus

LM2011028, research and development project

Name: RECETOX ? Národní infrastruktura pro výzkum toxických látek v prostředí

Investor: Ministry of Education, Youth and Sports of the CR

MUNI/C/1066/2015, interní kód MU

Name: Dvojvláknové zlomy u jedinců s velmi vysokou délkou života a možný vztah ke stravovacím návykům

Investor: Masaryk University, Rector's Program

Citovat

LENÁRT, Peter and Julie BIENERTOVÁ VAŠKŮ. Keeping up with the Red Queen: the pace of aging as an adaptation. In Suresh I.S. Rattan. 10th European Congress of Biogerontology combined with the 6th Biogerontological Meeting - The Future of Ageing. New York: Springer, 2017, p. 693-709. ISSN 1389-5729. Available from: https://dx.doi.org/10.1007/s10522-016-9674-4.

@inproceedings{1394992,
   author = {Lenárt, Peter and Bienertová Vašků, Julie},
   address = {New York},
   booktitle = {10th European Congress of Biogerontology combined with the 6th Biogerontological Meeting - The Future of Ageing},
   doi = {http://dx.doi.org/10.1007/s10522-016-9674-4},
   editor = {Suresh I.S. Rattan},
   keywords = {Aging; Evolution; Programmed aging; Red Queen; Pace of aging; Aging as an adaptation},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {New York},
   pages = {693-709},
   publisher = {Springer},
   title = {Keeping up with the Red Queen: the pace of aging as an adaptation},
   year = {2017}
}

TY  - JOUR
ID  - 1394992
AU  - Lenárt, Peter - Bienertová Vašků, Julie
PY  - 2017
TI  - Keeping up with the Red Queen: the pace of aging as an adaptation
PB  - Springer
CY  - New York
KW  - Aging
KW  - Evolution
KW  - Programmed aging
KW  - Red Queen
KW  - Pace of aging
KW  - Aging as an adaptation
N2  - For decades, a vast majority of biogerontologists assumed that aging is not and cannot be an adaptation. In recent years, however, several authors opposed this predominant view and repeatedly suggested that not only is aging an adaptation but that it is the result of a specific aging program. This issue almost instantaneously became somewhat controversial and many important authors produced substantial works refuting the notion of the aging program. In this article we review the current state of the debate and list the most important arguments proposed by both sides. Furthermore, although classical interpretations of the evolution of aging are in sharp contrast with the idea of programmed aging, we suggest that the truth might in fact very well lie somewhere in between. We also propose our own interpretation which states that although aging is in essence inevitable and results from damage accumulation rather than from a specific program, the actual rate of aging in nature may still be adaptive to some extent.
ER  -

LENÁRT, Peter and Julie BIENERTOVÁ VAŠKŮ. Keeping up with the Red Queen: the pace of aging as an adaptation. In Suresh I.S. Rattan. \textit{10th European Congress of Biogerontology combined with the 6th Biogerontological Meeting - The Future of Ageing}. New York: Springer, 2017, p.~693-709. ISSN~1389-5729. Available from: https://dx.doi.org/10.1007/s10522-016-9674-4.

Detailed Information on Publication Record