KAŠTOVSKÝ, Jakub, Petra BOŘILOVÁ LINHARTOVÁ, Kristína MUSILOVÁ, Lenka ŽÁČKOVÁ, Martina KUKLETOVÁ, Lubomír KUKLA and Lydie IZAKOVIČOVÁ HOLLÁ. Lack of Association between BMP2/DLX3 Gene Polymorphisms and Dental Caries in Primary and Permanent Dentitions. Caries Research. Basel: Karger, 2017, vol. 51, No 6, p. 590-595. ISSN 0008-6568. Available from: https://dx.doi.org/10.1159/000479828.
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Basic information
Original name Lack of Association between BMP2/DLX3 Gene Polymorphisms and Dental Caries in Primary and Permanent Dentitions
Name in Czech BMP2/DLX3 genové polymorfizmy a zubní kaz v dočasné a stálé dentici
Authors KAŠTOVSKÝ, Jakub (203 Czech Republic, belonging to the institution), Petra BOŘILOVÁ LINHARTOVÁ (203 Czech Republic, belonging to the institution), Kristína MUSILOVÁ (203 Czech Republic, belonging to the institution), Lenka ŽÁČKOVÁ (203 Czech Republic, belonging to the institution), Martina KUKLETOVÁ (203 Czech Republic, belonging to the institution), Lubomír KUKLA (203 Czech Republic, belonging to the institution) and Lydie IZAKOVIČOVÁ HOLLÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition Caries Research, Basel, Karger, 2017, 0008-6568.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30208 Dentistry, oral surgery and medicine
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.188
RIV identification code RIV/00216224:14110/17:00095175
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1159/000479828
UT WoS 000419790800006
Keywords in English BMP2; Case-control study; Dental caries; DLX3; Gene polymorphism
Tags EL OK, podil
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 18/3/2018 17:18.
Abstract
The aim of this study was to analyze the association between BMP2 (rs1884302) and DLX3 (rs2278163) gene polymorphisms and dental caries in primary and permanent dentitions. A total of 914 subjects were genotyped by the TaqMan methods: 176 caries-free children (with Decayed/Missing/Filled Teeth, DMFT = 0), 542 patients with dental caries in permanent dentition (DMFT >/= 1), 83 caries-free children with primary teeth (with decayed/missing/filled teeth, dmft = 0), and 113 children with early childhood caries (ECC, dmft >/= 1). There were no significant differences in allele/genotype frequencies between patients with caries in permanent dentition/ECC and caries-free children or between patients with very low (DMFT = 0-2), low (DMFT = 3-5), moderate (DMFT = 6-8), or high (DMFT >/= 9) caries experience. Variability in BMP2 and DLX3 was not associated with caries in the Czech population.
Links
EF16_013/0001761, research and development projectName: RECETOX RI
GB14-37368G, research and development projectName: Centrum orofaciálního vývoje a regenerace
Investor: Czech Science Foundation
LM2015051, research and development projectName: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX RI)
Investor: Ministry of Education, Youth and Sports of the CR
MUNI/A/0948/2016, interní kód MUName: Nemoci dutiny ústní – etiopatogeneze, klinické projevy, diagnostika a léčba
Investor: Masaryk University, Category A
NV17-30439A, research and development projectName: Moderní biotechnologické a behaviorální přístupy ve výzkumu zubního kazu a strategie jeho prevence
ROZV/24/LF/2016, interní kód MUName: LF - Příspěvek IP 2016
Investor: Ministry of Education, Youth and Sports of the CR
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