J 2017

Reference values of cardio-ankle vascular index in a random sample of a white population

WOHLFAHRT, P., R. CIFKOVA, N. MOVSISYAN, Šárka KUNZOVÁ, Jiří LEŠOVSKÝ et. al.

Basic information

Original name

Reference values of cardio-ankle vascular index in a random sample of a white population

Authors

WOHLFAHRT, P. (203 Czech Republic), R. CIFKOVA (203 Czech Republic), N. MOVSISYAN (203 Czech Republic), Šárka KUNZOVÁ (203 Czech Republic), Jiří LEŠOVSKÝ (203 Czech Republic), M. HOMOLKA (203 Czech Republic), Vladimír SOŠKA (203 Czech Republic, belonging to the institution), Petr DOBŠÁK (203 Czech Republic, belonging to the institution), F. LOPEZ-JIMENEZ (840 United States of America) and Ondřej SOCHOR (203 Czech Republic, guarantor)

Edition

journal of Hypertension, PHILADELPHIA, William and Wilkins, 2017, 0263-6352

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 4.099

RIV identification code

RIV/00216224:14110/17:00098395

Organization unit

Faculty of Medicine

DOI

UT WoS

000411899000018

Keywords in English

arterial stiffness; cardio-ankle vascular index; reference values; white population

Tags

Tags

International impact, Reviewed
Změněno: 20/3/2018 18:43, Soňa Böhmová

Abstract

V originále

Objectives: Cardio-ankle vascular index (CAVI), a parameter of arterial stiffness, has been increasingly used for cardiovascular risk estimation. Currently used CAVI reference values are derived from the Japanese population. It is not clear whether the same reference values can be used in the white population. The aim of the present study was to describe cardiovascular risk factors influencing CAVI and to establish CAVI reference values. Methods: A total of 2160 individuals randomly selected from the Brno city population aged 25-65 years were examined. Of these, 1347 patients were free from cardiovascular disease, nondiabetic and untreated by antihypertensive or lipid-lowering drugs, forming the reference value population. CAVI was measured using the VaSera VS-1000 device (Fukuda Denshi, Tokyo, Japan). Results: At each blood pressure (BP) level, there was a quadratic association between CAVI and age, except for a linear association in the optimal BP group. Although there was no association between BP and CAVI in younger patients, there was a linear association between CAVI and BP after 40 years of age. Reference values by age and sex were established. In each age group, except for the male 60-65-year group, reference values in our population were lower than in the Japanese one with the difference ranging from -0.29 to 0.21 for men, and from -0.38 to -0.03 for women. Conclusion: This is the first study providing CAVI reference values in a random sample of the white population. Our results suggest that the currently used values slightly overestimate CAVI in younger white, possibly underestimating cardiovascular risk.