A-waves increase the risk of developing neuropathy

J 2017

A-waves increase the risk of developing neuropathy

ŠROTOVÁ, Iva, Eva VLČKOVÁ, Ladislav DUŠEK and Josef BEDNAŘÍK

Basic information

Original name

A-waves increase the risk of developing neuropathy

Authors

ŠROTOVÁ, Iva (203 Czech Republic, belonging to the institution), Eva VLČKOVÁ (203 Czech Republic, guarantor, belonging to the institution), Ladislav DUŠEK (203 Czech Republic, belonging to the institution) and Josef BEDNAŘÍK (203 Czech Republic, belonging to the institution)

Edition

Brain and Behavior, Hoboken, John Wiley and Sons Inc. 2017, 2162-3279

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.219

RIV identification code

RIV/00216224:14110/17:00098486

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1002/brb3.760

UT WoS

000407906200017

Keywords in English

A-wave; electromyography; F-wave; late response; nerve conduction study; neurography; neuropathy

Abstract

V originále

Introduction: A-waves, which are observed following the M-wave during motor nerve conduction studies (NCS), are late responses that are frequently found in many types of neurogenic disorders. However, A-waves are also common in healthy individuals, where their significance remains unclear. The aim of this study was to examine whether the occurrence of A-waves does in fact represent an increased risk for the future development of changes upon NCS or needle electromyography (EMG) in the corresponding nerve. Methods: Nerve conduction studies/needle electromyography findings at control examination were evaluated in relation to the occurrence of initial A-waves in 327 individuals who had undergone repeated NCS/EMG examination and exhibited normal initial findings, with or without the occurrence of A-waves as the only acceptable abnormality. Results: The odds ratio, which reflects the predictive power of the occurrence of A-waves at the initial testing for the development of an abnormality (neuropathy or radiculopathy) at the follow-up examination, ranged from 2.7 (p=.041) in the tibial nerve and 3.9 (p=.034) in peroneal one, to 30.0 (p=.002) in the ulnar nerve. Conclusions: A-waves constitute an initial abnormality in all nerves, and they may be predictive for the future development of broader NCS/EMG abnormalities in the corresponding nerve.

Links

MUNI/A/1072/2015, interní kód MU

Name: Diagnostika a patofyziologie neuropatické bolesti (Acronym: PNB)

Investor: Masaryk University, Category A

Citovat

ŠROTOVÁ, Iva, Eva VLČKOVÁ, Ladislav DUŠEK and Josef BEDNAŘÍK. A-waves increase the risk of developing neuropathy. Brain and Behavior. Hoboken: John Wiley and Sons Inc., 2017, vol. 7, No 8, p. 1-7. ISSN 2162-3279. Available from: https://dx.doi.org/10.1002/brb3.760.

@article{1396966,
   author = {Šrotová, Iva and Vlčková, Eva and Dušek, Ladislav and Bednařík, Josef},
   article_location = {Hoboken},
   article_number = {8},
   doi = {http://dx.doi.org/10.1002/brb3.760},
   keywords = {A-wave; electromyography; F-wave; late response; nerve conduction study; neurography; neuropathy},
   language = {eng},
   issn = {2162-3279},
   journal = {Brain and Behavior},
   title = {A-waves increase the risk of developing neuropathy},
   volume = {7},
   year = {2017}
}

TY  - JOUR
ID  - 1396966
AU  - Šrotová, Iva - Vlčková, Eva - Dušek, Ladislav - Bednařík, Josef
PY  - 2017
TI  - A-waves increase the risk of developing neuropathy
JF  - Brain and Behavior
VL  - 7
IS  - 8
SP  - 1-7
EP  - 1-7
PB  - John Wiley and Sons Inc.
SN  - 21623279
KW  - A-wave
KW  - electromyography
KW  - F-wave
KW  - late response
KW  - nerve conduction study
KW  - neurography
KW  - neuropathy
N2  - Introduction: A-waves, which are observed following the M-wave during motor nerve conduction studies (NCS), are late responses that are frequently found in many types of neurogenic disorders. However, A-waves are also common in healthy individuals, where their significance remains unclear. The aim of this study was to examine whether the occurrence of A-waves does in fact represent an increased risk for the future development of changes upon NCS or needle electromyography (EMG) in the corresponding nerve. Methods: Nerve conduction studies/needle electromyography findings at control examination were evaluated in relation to the occurrence of initial A-waves in 327 individuals who had undergone repeated NCS/EMG examination and exhibited normal initial findings, with or without the occurrence of A-waves as the only acceptable abnormality. Results: The odds ratio, which reflects the predictive power of the occurrence of A-waves at the initial testing for the development of an abnormality (neuropathy or radiculopathy) at the follow-up examination, ranged from 2.7 (p=.041) in the tibial nerve and 3.9 (p=.034) in peroneal one, to 30.0 (p=.002) in the ulnar nerve. Conclusions: A-waves constitute an initial abnormality in all nerves, and they may be predictive for the future development of broader NCS/EMG abnormalities in the corresponding nerve.
ER  -

ŠROTOVÁ, Iva, Eva VLČKOVÁ, Ladislav DUŠEK and Josef BEDNAŘÍK. A-waves increase the risk of developing neuropathy. \textit{Brain and Behavior}. Hoboken: John Wiley and Sons Inc., 2017, vol.~7, No~8, p.~1-7. ISSN~2162-3279. Available from: https://dx.doi.org/10.1002/brb3.760.

Detailed Information on Publication Record