ŠROTOVÁ, Iva, Eva VLČKOVÁ, Ladislav DUŠEK and Josef BEDNAŘÍK. A-waves increase the risk of developing neuropathy. Brain and Behavior. Hoboken: John Wiley and Sons Inc., 2017, vol. 7, No 8, p. 1-7. ISSN 2162-3279. Available from: https://dx.doi.org/10.1002/brb3.760.
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Basic information
Original name A-waves increase the risk of developing neuropathy
Authors ŠROTOVÁ, Iva (203 Czech Republic, belonging to the institution), Eva VLČKOVÁ (203 Czech Republic, guarantor, belonging to the institution), Ladislav DUŠEK (203 Czech Republic, belonging to the institution) and Josef BEDNAŘÍK (203 Czech Republic, belonging to the institution).
Edition Brain and Behavior, Hoboken, John Wiley and Sons Inc. 2017, 2162-3279.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30103 Neurosciences
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.219
RIV identification code RIV/00216224:14110/17:00098486
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1002/brb3.760
UT WoS 000407906200017
Keywords in English A-wave; electromyography; F-wave; late response; nerve conduction study; neurography; neuropathy
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 21/3/2018 17:52.
Abstract
Introduction: A-waves, which are observed following the M-wave during motor nerve conduction studies (NCS), are late responses that are frequently found in many types of neurogenic disorders. However, A-waves are also common in healthy individuals, where their significance remains unclear. The aim of this study was to examine whether the occurrence of A-waves does in fact represent an increased risk for the future development of changes upon NCS or needle electromyography (EMG) in the corresponding nerve. Methods: Nerve conduction studies/needle electromyography findings at control examination were evaluated in relation to the occurrence of initial A-waves in 327 individuals who had undergone repeated NCS/EMG examination and exhibited normal initial findings, with or without the occurrence of A-waves as the only acceptable abnormality. Results: The odds ratio, which reflects the predictive power of the occurrence of A-waves at the initial testing for the development of an abnormality (neuropathy or radiculopathy) at the follow-up examination, ranged from 2.7 (p=.041) in the tibial nerve and 3.9 (p=.034) in peroneal one, to 30.0 (p=.002) in the ulnar nerve. Conclusions: A-waves constitute an initial abnormality in all nerves, and they may be predictive for the future development of broader NCS/EMG abnormalities in the corresponding nerve.
Links
MUNI/A/1072/2015, interní kód MUName: Diagnostika a patofyziologie neuropatické bolesti (Acronym: PNB)
Investor: Masaryk University, Category A
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