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@article{1397230,
author = {Vetrovsky, T. and Siranec, M. and Pařenica, Jiří and Griva, M. and Stastny, J. and Precek, J. and Pelouch, R. and Bunc, V. and Linhart, A. and Belohlavek, J.},
article_location = {London, England},
article_number = {153},
doi = {http://dx.doi.org/10.1186/s12967-017-1257-x},
keywords = {Chronic heart failure; Physical activity; Walking; Functional capacity; Pedometer; 6-min walk test; NT-proBNP},
language = {eng},
issn = {1479-5876},
journal = {Journal of Translational Medicine},
title = {Effect of a 6-month pedometer-based walking intervention on functional capacity in patients with chronic heart failure with reduced (HFrEF) and with preserved (HFpEF) ejection fraction: study protocol for two multicenter randomized controlled trials},
url = {http://dx.doi.org/10.1186/s12967-017-1257-x},
volume = {15},
year = {2017}
}
TY - JOUR
ID - 1397230
AU - Vetrovsky, T. - Siranec, M. - Pařenica, Jiří - Griva, M. - Stastny, J. - Precek, J. - Pelouch, R. - Bunc, V. - Linhart, A. - Belohlavek, J.
PY - 2017
TI - Effect of a 6-month pedometer-based walking intervention on functional capacity in patients with chronic heart failure with reduced (HFrEF) and with preserved (HFpEF) ejection fraction: study protocol for two multicenter randomized controlled trials
JF - Journal of Translational Medicine
VL - 15
IS - 153
SP - 1-10
EP - 1-10
PB - BIOMED CENTRAL LTD
SN - 14795876
KW - Chronic heart failure
KW - Physical activity
KW - Walking
KW - Functional capacity
KW - Pedometer
KW - 6-min walk test
KW - NT-proBNP
UR - http://dx.doi.org/10.1186/s12967-017-1257-x
L2 - http://dx.doi.org/10.1186/s12967-017-1257-x
N2 - Background: Regular physical activity is recommended for patients with chronic heart failure to improve their functional capacity, and walking is a popular, effective, and safe form of physical activity. Pedometers have shown potential to increase the amount of walking across a range of chronic diseases, but it is unknown whether a pedometerbased intervention improves functional capacity and neurohumoral modulation in heart failure patients. Methods: Two multicenter randomized controlled trials will be conducted in parallel: one in patients with chronic heart failure with reduced ejection fraction (HFrEF), the other in patients with chronic heart failure with preserved ejection fraction (HFpEF). Each trial will consist of a 6-month intervention with an assessment at baseline, at 3 months, at the end of the intervention, and 6 months after completing the intervention. Each trial will aim to include a total of 200 physically inactive participants with chronic heart failure who will be randomly assigned to intervention or control arms. The 6-month intervention will consist of an individualized pedometer-based walking program with weekly step goals, behavioral face-to-face sessions with a physician, and regular telephone calls with a research nurse. The intervention will be based on effective behavioral principles (goal setting, self-monitoring, personalized feedback). The primary outcome is the change in 6-min walk distance at the end of the 6-month intervention. Secondary outcomes include changes in serum biomarkers levels, pulmonary congestion assessed by ultrasound, average daily step count measured by accelerometry, anthropometric measures, symptoms of depression, health-related quality of life, self-efficacy, and MAGGIC risk score. Discussion: To our knowledge, these are the first studies to evaluate a pedometer-based walking intervention in patients with chronic heart failure with either reduced or preserved ejection fraction. The studies will contribute to a better understanding of physical activity promotion in heart failure patients to inform future physical activity recommendations and heart failure guidelines.
ER -
VETROVSKY, T., M. SIRANEC, Jiří PAŘENICA, M. GRIVA, J. STASTNY, J. PRECEK, R. PELOUCH, V. BUNC, A. LINHART a J. BELOHLAVEK. Effect of a 6-month pedometer-based walking intervention on functional capacity in patients with chronic heart failure with reduced (HFrEF) and with preserved (HFpEF) ejection fraction: study protocol for two multicenter randomized controlled trials. \textit{Journal of Translational Medicine}. London, England: BIOMED CENTRAL LTD, roč.~15, č.~153, s.~1-10. ISSN~1479-5876. doi:10.1186/s12967-017-1257-x. 2017.
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