Lze zlepšit komplianci pacientů k dlouhodobé terapii statiny?

SOŠKA, Vladimír and Ondřej KYSELÁK. Lze zlepšit komplianci pacientů k dlouhodobé terapii statiny? (Is it possible to improve long-term compliance of patients to statin therapy?). Vnitřní lékařství. Praha: Česká lékařská společnost J.E. Purkyně, 2017, vol. 63, No 10, p. 663-666. ISSN 0042-773X.

Basic information

• Original name: Lze zlepšit komplianci pacientů k dlouhodobé terapii statiny?
• Name (in English): Is it possible to improve long-term compliance of patients to statin therapy?
• Authors: SOŠKA, Vladimír (203 Czech Republic, guarantor, belonging to the institution) and Ondřej KYSELÁK (203 Czech Republic).
• Edition: Vnitřní lékařství, Praha, Česká lékařská společnost J.E. Purkyně, 2017, 0042-773X.

Other information

• Original language: Czech
• Type of outcome: Article in a journal
• Field of Study: 30200 3.2 Clinical medicine
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14110/17:00098601
• Organization unit: Faculty of Medicine
• Keywords in English: Compliance; Creatinkinase; Diabetes mellitus; Ldl-cholesterol; Statins
• Tags: EL OK
• Tags: International impact, Reviewed

Abstract

Statins are key drugs for patients in secondary prevention of cardiovascular disease, as well as for primary prevention patients at high or very high risk of fatal cardiovascular events. However, long-term compliance of patients to statin therapy is relatively low, decreasing with the time of statin use; moreover a significant proportion of patients stop statins medication over the course of several years. To the early termination of statin treatment often contributes apprehension of the occurence of statin's side effects (i.g. increased creatine kinase in the blood and muscle problems), although these symptoms are usually not causally related to statin therapy. To the low compliance may also contribute administration of statins in the evening hours, as well as the fear of developing diabetes or drug interactions. The above issues are discussed in the text of this article.

Abstract (in English)

Statins are key drugs for patients in secondary prevention of cardiovascular disease, as well as for primary prevention patients at high or very high risk of fatal cardiovascular events. However, long-term compliance of patients to statin therapy is relatively low, decreasing with the time of statin use; moreover a significant proportion of patients stop statins medication over the course of several years. To the early termination of statin treatment often contributes apprehension of the occurence of statin's side effects (i.g. increased creatine kinase in the blood and muscle problems), although these symptoms are usually not causally related to statin therapy. To the low compliance may also contribute administration of statins in the evening hours, as well as the fear of developing diabetes or drug interactions. The above issues are discussed in the text of this article.