Lze zlepšit komplianci pacientů k dlouhodobé terapii statiny?

SOŠKA, Vladimír and Ondřej KYSELÁK. Lze zlepšit komplianci pacientů k dlouhodobé terapii statiny? (Is it possible to improve long-term compliance of patients to statin therapy?). Vnitřní lékařství. Praha: Česká lékařská společnost J.E. Purkyně, 2017, vol. 63, No 10, p. 663-666. ISSN 0042-773X.

Basic information

Original name

Lze zlepšit komplianci pacientů k dlouhodobé terapii statiny?

Name (in English)

Is it possible to improve long-term compliance of patients to statin therapy?

Authors

SOŠKA, Vladimír (203 Czech Republic, guarantor, belonging to the institution) and Ondřej KYSELÁK (203 Czech Republic)

Edition

Vnitřní lékařství, Praha, Česká lékařská společnost J.E. Purkyně, 2017, 0042-773X

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Other information

Language

Czech

Type of outcome

Článek v odborném periodiku

Field of Study

30200 3.2 Clinical medicine

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/17:00098601

Organization unit

Faculty of Medicine

Keywords in English

Compliance; Creatinkinase; Diabetes mellitus; Ldl-cholesterol; Statins

Tags

EL OK

Tags

International impact, Reviewed

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Abstract

V originále

Statins are key drugs for patients in secondary prevention of cardiovascular disease, as well as for primary prevention patients at high or very high risk of fatal cardiovascular events. However, long-term compliance of patients to statin therapy is relatively low, decreasing with the time of statin use; moreover a significant proportion of patients stop statins medication over the course of several years. To the early termination of statin treatment often contributes apprehension of the occurence of statin's side effects (i.g. increased creatine kinase in the blood and muscle problems), although these symptoms are usually not causally related to statin therapy. To the low compliance may also contribute administration of statins in the evening hours, as well as the fear of developing diabetes or drug interactions. The above issues are discussed in the text of this article.

In English

Statins are key drugs for patients in secondary prevention of cardiovascular disease, as well as for primary prevention patients at high or very high risk of fatal cardiovascular events. However, long-term compliance of patients to statin therapy is relatively low, decreasing with the time of statin use; moreover a significant proportion of patients stop statins medication over the course of several years. To the early termination of statin treatment often contributes apprehension of the occurence of statin's side effects (i.g. increased creatine kinase in the blood and muscle problems), although these symptoms are usually not causally related to statin therapy. To the low compliance may also contribute administration of statins in the evening hours, as well as the fear of developing diabetes or drug interactions. The above issues are discussed in the text of this article.