Immunomodulatory effects of stem cells: Therapeutic option for
neurodegenerative disorders

J 2017

Immunomodulatory effects of stem cells: Therapeutic option for neurodegenerative disorders

CAPRNDA, M., P.. KUBATKA, K. GAZDIKOVA, I. GASPAROVA, V. VALENTOVA et. al.

Basic information

Original name

Immunomodulatory effects of stem cells: Therapeutic option for neurodegenerative disorders

Authors

CAPRNDA, M. (703 Slovakia), P.. KUBATKA (703 Slovakia), K. GAZDIKOVA (703 Slovakia), I. GASPAROVA (703 Slovakia), V. VALENTOVA (703 Slovakia), N. STOLLAROVA (703 Slovakia), G. LA ROCCA (380 Italy), N. KOBYLIAK (804 Ukraine), J. DRAGASEK (703 Slovakia), I. MOZOS (642 Romania), R. PROSECKY (203 Czech Republic), D. SINISCALCO (380 Italy), D. BUSSELBERG (634 Qatar), L. RODRIGO (724 Spain) and Peter KRUŽLIAK (703 Slovakia, guarantor, belonging to the institution)

Edition

BIOMEDICINE & PHARMACOTHERAPY, PARIS, ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017, 0753-3322

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

France

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 3.457

RIV identification code

RIV/00216224:14110/17:00098636

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.biopha.2017.04.034

UT WoS

000406399900008

Keywords in English

Stem cell therapy; Neurodegenerative disorders; Regenerative medicine

Abstract

V originále

Stem cells have the capability of self-renewal and can differentiate into different cell types that might be used in regenerative medicine. Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), multiple sclerosis (MS), and amyotrophic lateral sclerosis (ALS) currently lack effective treatments. Although stem cell therapy is still on the way from bench to bedside, we consider that it might provide new hope for patients suffering with neurodegenerative diseases. In this article, we will give an overview of recent studies on the potential therapeutic use of mesenchymal stem cells (MSCs), neural stem cells (NSCs), embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and perinatal stem cells to neurodegenerative disorders and we will describe their immunomodulatory mechanisms of action in specific therapeutic modalities. (C) 2017 Elsevier Masson SAS. All rights reserved.

Citovat

CAPRNDA, M., P.. KUBATKA, K. GAZDIKOVA, I. GASPAROVA, V. VALENTOVA, N. STOLLAROVA, G. LA ROCCA, N. KOBYLIAK, J. DRAGASEK, I. MOZOS, R. PROSECKY, D. SINISCALCO, D. BUSSELBERG, L. RODRIGO and Peter KRUŽLIAK. Immunomodulatory effects of stem cells: Therapeutic option for neurodegenerative disorders. BIOMEDICINE & PHARMACOTHERAPY. PARIS: ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017, vol. 91, JUL 2017, p. 60-69. ISSN 0753-3322. Available from: https://dx.doi.org/10.1016/j.biopha.2017.04.034.

@article{1398271,
   author = {Caprnda, M. and Kubatka, P.. and Gazdikova, K. and Gasparova, I. and Valentova, V. and Stollarova, N. and La Rocca, G. and Kobyliak, N. and Dragasek, J. and Mozos, I. and Prosecky, R. and Siniscalco, D. and Busselberg, D. and Rodrigo, L. and Kružliak, Peter},
   article_location = {PARIS},
   article_number = {JUL 2017},
   doi = {http://dx.doi.org/10.1016/j.biopha.2017.04.034},
   keywords = {Stem cell therapy; Neurodegenerative disorders; Regenerative medicine},
   language = {eng},
   issn = {0753-3322},
   journal = {BIOMEDICINE & PHARMACOTHERAPY},
   title = {Immunomodulatory effects of stem cells: Therapeutic option for neurodegenerative disorders},
   volume = {91},
   year = {2017}
}

TY  - JOUR
ID  - 1398271
AU  - Caprnda, M. - Kubatka, P.. - Gazdikova, K. - Gasparova, I. - Valentova, V. - Stollarova, N. - La Rocca, G. - Kobyliak, N. - Dragasek, J. - Mozos, I. - Prosecky, R. - Siniscalco, D. - Busselberg, D. - Rodrigo, L. - Kružliak, Peter
PY  - 2017
TI  - Immunomodulatory effects of stem cells: Therapeutic option for neurodegenerative disorders
JF  - BIOMEDICINE & PHARMACOTHERAPY
VL  - 91
IS  - JUL 2017
SP  - 60-69
EP  - 60-69
PB  - ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SN  - 07533322
KW  - Stem cell therapy
KW  - Neurodegenerative disorders
KW  - Regenerative medicine
N2  - Stem cells have the capability of self-renewal and can differentiate into different cell types that might be used in regenerative medicine. Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), multiple sclerosis (MS), and amyotrophic lateral sclerosis (ALS) currently lack effective treatments. Although stem cell therapy is still on the way from bench to bedside, we consider that it might provide new hope for patients suffering with neurodegenerative diseases. In this article, we will give an overview of recent studies on the potential therapeutic use of mesenchymal stem cells (MSCs), neural stem cells (NSCs), embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and perinatal stem cells to neurodegenerative disorders and we will describe their immunomodulatory mechanisms of action in specific therapeutic modalities. (C) 2017 Elsevier Masson SAS. All rights reserved.
ER  -

CAPRNDA, M., P.. KUBATKA, K. GAZDIKOVA, I. GASPAROVA, V. VALENTOVA, N. STOLLAROVA, G. LA ROCCA, N. KOBYLIAK, J. DRAGASEK, I. MOZOS, R. PROSECKY, D. SINISCALCO, D. BUSSELBERG, L. RODRIGO and Peter KRUŽLIAK. Immunomodulatory effects of stem cells: Therapeutic option for neurodegenerative disorders. \textit{BIOMEDICINE \&{}amp; PHARMACOTHERAPY}. PARIS: ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017, vol.~91, JUL 2017, p.~60-69. ISSN~0753-3322. Available from: https://dx.doi.org/10.1016/j.biopha.2017.04.034.

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