CAPRNDA, M., P.. KUBATKA, K. GAZDIKOVA, I. GASPAROVA, V. VALENTOVA, N. STOLLAROVA, G. LA ROCCA, N. KOBYLIAK, J. DRAGASEK, I. MOZOS, R. PROSECKY, D. SINISCALCO, D. BUSSELBERG, L. RODRIGO and Peter KRUŽLIAK. Immunomodulatory effects of stem cells: Therapeutic option for neurodegenerative disorders. BIOMEDICINE & PHARMACOTHERAPY. PARIS: ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017, vol. 91, JUL 2017, p. 60-69. ISSN 0753-3322. Available from: https://dx.doi.org/10.1016/j.biopha.2017.04.034.
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Basic information
Original name Immunomodulatory effects of stem cells: Therapeutic option for neurodegenerative disorders
Authors CAPRNDA, M. (703 Slovakia), P.. KUBATKA (703 Slovakia), K. GAZDIKOVA (703 Slovakia), I. GASPAROVA (703 Slovakia), V. VALENTOVA (703 Slovakia), N. STOLLAROVA (703 Slovakia), G. LA ROCCA (380 Italy), N. KOBYLIAK (804 Ukraine), J. DRAGASEK (703 Slovakia), I. MOZOS (642 Romania), R. PROSECKY (203 Czech Republic), D. SINISCALCO (380 Italy), D. BUSSELBERG (634 Qatar), L. RODRIGO (724 Spain) and Peter KRUŽLIAK (703 Slovakia, guarantor, belonging to the institution).
Edition BIOMEDICINE & PHARMACOTHERAPY, PARIS, ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017, 0753-3322.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30104 Pharmacology and pharmacy
Country of publisher France
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 3.457
RIV identification code RIV/00216224:14110/17:00098636
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.biopha.2017.04.034
UT WoS 000406399900008
Keywords in English Stem cell therapy; Neurodegenerative disorders; Regenerative medicine
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 18/3/2018 23:02.
Abstract
Stem cells have the capability of self-renewal and can differentiate into different cell types that might be used in regenerative medicine. Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), multiple sclerosis (MS), and amyotrophic lateral sclerosis (ALS) currently lack effective treatments. Although stem cell therapy is still on the way from bench to bedside, we consider that it might provide new hope for patients suffering with neurodegenerative diseases. In this article, we will give an overview of recent studies on the potential therapeutic use of mesenchymal stem cells (MSCs), neural stem cells (NSCs), embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and perinatal stem cells to neurodegenerative disorders and we will describe their immunomodulatory mechanisms of action in specific therapeutic modalities. (C) 2017 Elsevier Masson SAS. All rights reserved.
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