Mechanical thrombectomy performs similarly in real world
practice: a 2016 nationwide study from the Czech Republic

J 2018

Mechanical thrombectomy performs similarly in real world practice: a 2016 nationwide study from the Czech Republic

VOLNÝ, Ondřej, Antonin KRAJINA, Silvie BELASKOVA, Michal BAR, Petra CIMFLOVÁ et. al.

Basic information

Original name

Mechanical thrombectomy performs similarly in real world practice: a 2016 nationwide study from the Czech Republic

Authors

VOLNÝ, Ondřej (203 Czech Republic, guarantor, belonging to the institution), Antonin KRAJINA (203 Czech Republic), Silvie BELASKOVA (203 Czech Republic), Michal BAR (203 Czech Republic), Petra CIMFLOVÁ (203 Czech Republic, belonging to the institution), Roman HERZIG (203 Czech Republic), Daniel SANAK (203 Czech Republic), Ales TOMEK (203 Czech Republic), Martin KOCHER (203 Czech Republic), Miroslav ROCEK (203 Czech Republic), Radek PADR (203 Czech Republic), Filip CIHLAR (203 Czech Republic), Miroslava NEVSIMALOVA (203 Czech Republic), Lubomir JURAK (203 Czech Republic), Roman HAVLICEK (203 Czech Republic), Martin KOVAR (203 Czech Republic), Petr SEVCIK (203 Czech Republic), Vladimir ROHAN (203 Czech Republic), Jan FIKSA (203 Czech Republic), Bijoy K. MENON (124 Canada) and Robert MIKULÍK (203 Czech Republic, belonging to the institution)

Edition

Journal of NeuroInterventional Surgery, London, BMJ PUBLISHING GROUP, 2018, 1759-8478

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 3.925

RIV identification code

RIV/00216224:14110/18:00102128

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1136/neurintsurg-2017-013534

UT WoS

000442392200010

Keywords in English

mechanical thrombectomy

Abstract

V originále

Background Randomized clinical trials have proven mechanical thrombectomy (MT) to be a highly effective and safe treatment in acute stroke. The purpose of this study was to compare neurothrombectomy data from the Czech Republic (CR) with data from the HERMES meta-analysis. Methods A vailable nationwide data for the CR from 2016 from the Safe Implementation of Treatments in Stroke-Thrombectomy (SITS-TBY) registry for patients with terminal internal carotid artery (ICA) and/or middle cerebral artery (MCA) occlusions were compared with data from HERMES. CR and HERMES patients were comparable in age, sex, and baseline National Institutes of Health Stroke Scale scores. Results From a total of 1053 MTs performed in the CR, 845 (80%) were reported in the SITS-TBY. From these, 604 (72%) were included in this study. Occlusion locations were as follows (CR vs HERMES): ICA 22% versus 21% (P=0.16), M1 MCA 62% versus 69% (P=0.004), and M2 MCA 16% versus 8% (P<0.0001). Intravenous thrombolysis was given to 76% versus 83% of patients, respectively (P=0.003). Median onset to reperfusion times were comparable: 232 versus 285 min, respectively (P=0.66). A modified Thrombolysis in Cerebral Infarction score of 2b/3 was achieved in 74% (433/584) versus 71% (390/549) of patients, respectively (OR 1.17, 95% CI 0.90-1.5, P=0.24). There was no statistically significant difference in the percentage of parenchymalhematoma type 2 (OR 1.12, 95% CI 0.66-1.90, P=0.68). A modified Rankin Scale score of 0-2 at 3 months was achieved in 48% (184/268) versus 46% (291/633) of patients, respectively (OR 0.92, 95% CI 0.71-1.18, P=0.48).

Citovat

VOLNÝ, Ondřej, Antonin KRAJINA, Silvie BELASKOVA, Michal BAR, Petra CIMFLOVÁ, Roman HERZIG, Daniel SANAK, Ales TOMEK, Martin KOCHER, Miroslav ROCEK, Radek PADR, Filip CIHLAR, Miroslava NEVSIMALOVA, Lubomir JURAK, Roman HAVLICEK, Martin KOVAR, Petr SEVCIK, Vladimir ROHAN, Jan FIKSA, Bijoy K. MENON and Robert MIKULÍK. Mechanical thrombectomy performs similarly in real world practice: a 2016 nationwide study from the Czech Republic. Journal of NeuroInterventional Surgery. London: BMJ PUBLISHING GROUP, 2018, vol. 10, No 8, p. 741-745. ISSN 1759-8478. Available from: https://dx.doi.org/10.1136/neurintsurg-2017-013534.

@article{1398286,
   author = {Volný, Ondřej and Krajina, Antonin and Belaskova, Silvie and Bar, Michal and Cimflová, Petra and Herzig, Roman and Sanak, Daniel and Tomek, Ales and Kocher, Martin and Rocek, Miroslav and Padr, Radek and Cihlar, Filip and Nevsimalova, Miroslava and Jurak, Lubomir and Havlicek, Roman and Kovar, Martin and Sevcik, Petr and Rohan, Vladimir and Fiksa, Jan and Menon, Bijoy K. and Mikulík, Robert},
   article_location = {London},
   article_number = {8},
   doi = {http://dx.doi.org/10.1136/neurintsurg-2017-013534},
   keywords = {mechanical thrombectomy},
   language = {eng},
   issn = {1759-8478},
   journal = {Journal of NeuroInterventional Surgery},
   title = {Mechanical thrombectomy performs similarly in real world practice: a 2016 nationwide study from the Czech Republic},
   volume = {10},
   year = {2018}
}

TY  - JOUR
ID  - 1398286
AU  - Volný, Ondřej - Krajina, Antonin - Belaskova, Silvie - Bar, Michal - Cimflová, Petra - Herzig, Roman - Sanak, Daniel - Tomek, Ales - Kocher, Martin - Rocek, Miroslav - Padr, Radek - Cihlar, Filip - Nevsimalova, Miroslava - Jurak, Lubomir - Havlicek, Roman - Kovar, Martin - Sevcik, Petr - Rohan, Vladimir - Fiksa, Jan - Menon, Bijoy K. - Mikulík, Robert
PY  - 2018
TI  - Mechanical thrombectomy performs similarly in real world practice: a 2016 nationwide study from the Czech Republic
JF  - Journal of NeuroInterventional Surgery
VL  - 10
IS  - 8
SP  - 741-745
EP  - 741-745
PB  - BMJ PUBLISHING GROUP
SN  - 17598478
KW  - mechanical thrombectomy
N2  - Background Randomized clinical trials have proven mechanical thrombectomy (MT) to be a highly effective and safe treatment in acute stroke. The purpose of this study was to compare neurothrombectomy data from the Czech Republic (CR) with data from the HERMES meta-analysis. Methods A vailable nationwide data for the CR from 2016 from the Safe Implementation of Treatments in Stroke-Thrombectomy (SITS-TBY) registry for patients with terminal internal carotid artery (ICA) and/or middle cerebral artery (MCA) occlusions were compared with data from HERMES. CR and HERMES patients were comparable in age, sex, and baseline National Institutes of Health Stroke Scale scores. Results From a total of 1053 MTs performed in the CR, 845 (80%) were reported in the SITS-TBY. From these, 604 (72%) were included in this study. Occlusion locations were as follows (CR vs HERMES): ICA 22% versus 21% (P=0.16), M1 MCA 62% versus 69% (P=0.004), and M2 MCA 16% versus 8% (P<0.0001). Intravenous thrombolysis was given to 76% versus 83% of patients, respectively (P=0.003). Median onset to reperfusion times were comparable: 232 versus 285 min, respectively (P=0.66). A modified Thrombolysis in Cerebral Infarction score of 2b/3 was achieved in 74% (433/584) versus 71% (390/549) of patients, respectively (OR 1.17, 95% CI 0.90-1.5, P=0.24). There was no statistically significant difference in the percentage of parenchymalhematoma type 2 (OR 1.12, 95% CI 0.66-1.90, P=0.68). A modified Rankin Scale score of 0-2 at 3 months was achieved in 48% (184/268) versus 46% (291/633) of patients, respectively (OR 0.92, 95% CI 0.71-1.18, P=0.48).
ER  -

VOLNÝ, Ondřej, Antonin KRAJINA, Silvie BELASKOVA, Michal BAR, Petra CIMFLOVÁ, Roman HERZIG, Daniel SANAK, Ales TOMEK, Martin KOCHER, Miroslav ROCEK, Radek PADR, Filip CIHLAR, Miroslava NEVSIMALOVA, Lubomir JURAK, Roman HAVLICEK, Martin KOVAR, Petr SEVCIK, Vladimir ROHAN, Jan FIKSA, Bijoy K. MENON and Robert MIKULÍK. Mechanical thrombectomy performs similarly in real world practice: a 2016 nationwide study from the Czech Republic. \textit{Journal of NeuroInterventional Surgery}. London: BMJ PUBLISHING GROUP, 2018, vol.~10, No~8, p.~741-745. ISSN~1759-8478. Available from: https://dx.doi.org/10.1136/neurintsurg-2017-013534.

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