Toxic epidermal necrolysis (TEN) is a rare, life-threatening condition, which is caused by the development of massive apoptosis in the dermoepidermal junction [1]. This apoptosis is mainly caused by caspase mechanisms, which are affected by the activity of T-lymphocytes (CD4+ and CD8+), NK cells, or the bond of CD95L to CD95R [2]. Noncaspase mechanisms are also applied in the TEN pathophysiology, e.g., production of granzyme B CD8+ T lymphocytes or NK cells.