KALA, Petr, P. CERVINKA, M. JAKL, Jan KAŇOVSKÝ, A. KUPEC, R. SPACEK, M. KVASNAK, Martin POLOCZEK, M. CERVINKOVA, H. BEZERRA, Z. VALENTA, G.F. ATTIZZANI, A. SCHNELL, L. HONG and M.A. COSTA. OCT guidance during stent implantation in primary PCI: A randomized multicenter study with nine months of optical coherence tomography follow-up. Online. International Journal of Cardiology. Clare (Ireland): Elsevier Ireland Ltd., 2018, vol. 250, JAN 1 2018, p. 98-103. ISSN 0167-5273. Available from: https://dx.doi.org/10.1016/j.ijcard.2017.10.059. [citováno 2024-04-23]
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Basic information
Original name OCT guidance during stent implantation in primary PCI: A randomized multicenter study with nine months of optical coherence tomography follow-up
Authors KALA, Petr (203 Czech Republic, belonging to the institution), P. CERVINKA (203 Czech Republic, guarantor), M. JAKL (203 Czech Republic), Jan KAŇOVSKÝ (203 Czech Republic, belonging to the institution), A. KUPEC (203 Czech Republic), R. SPACEK (203 Czech Republic), M. KVASNAK (203 Czech Republic), Martin POLOCZEK (203 Czech Republic), M. CERVINKOVA (203 Czech Republic), H. BEZERRA (840 United States of America), Z. VALENTA (203 Czech Republic), G.F. ATTIZZANI (840 United States of America), A. SCHNELL (840 United States of America), L. HONG (840 United States of America) and M.A. COSTA (840 United States of America)
Edition International Journal of Cardiology, Clare (Ireland), Elsevier Ireland Ltd. 2018, 0167-5273.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher Ireland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 3.471
RIV identification code RIV/00216224:14110/18:00102131
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.ijcard.2017.10.059
UT WoS 000415822100021
Keywords in English Optical coherence tomography; OCT; Primary PCI; ST-segment elevation myocardial infarction; Drug-eluting stents
Tags 14110211, EL OK, rivok
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 10/2/2019 17:03.
Abstract
Aims: To assess the possible merits of optical coherence tomography (OCT) guidance in primary percutaneous coronary intervention (pPCI). Methods and results: 201 patients with ST-elevation myocardial infarction (STEMI) were enrolled in this study. Patients were randomized either to pPCI alone (angio-guided group, n = 96) or to pPCI with OCT guidance (OCT-guided group, n = 105) and also either to biolimus A9 or to everolimus-eluting stent implantation. All patients were scheduled for nine months of follow-up angiography and OCT study. OCT guidance led to post-pPCI optimization in 29% of cases (59% malapposition and 41% dissections). No complications were found related to the OCT study. OCT analysis at ninemonths showed significantly less in-segment area of stenosis (6% [-11, 19] versus 18% [3, 33]; p = 0.0002) in favor of the OCT-guided group. The rate major adverse cardiovascular events were comparable at nine months in both groups (3% in the OCT group versus 2% in the angio-guided group; p = 0.87). Conclusions: This study demonstrates the safety of OCT guidance during pPCI. The use of OCT optimized stent deployment in 1/3 of patients in this clinical scenario and significantly reduced in-segment area of stenosis at nine months of follow-up. Whether such improvements in OCT endpoints will have a positive impact on late clinical outcomes, they demand both a larger and longer-term follow-up study. (C) 2017 Elsevier B.V. All rights reserved.
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