Periorbital Allergic Contact Dermatitis - The Most Common Allergens in the Czech Republic

NEČAS, Miroslav and Eliška DASTYCHOVÁ. Periorbital Allergic Contact Dermatitis - The Most Common Allergens in the Czech Republic. International Journal of Ophthalmology and Clinical Research. Wilmington: ClinMed International Library, 2017, vol. 4, No 3, p. 1-5. ISSN 2378-346X.

Basic information

Original name

Periorbital Allergic Contact Dermatitis - The Most Common Allergens in the Czech Republic

Authors

NEČAS, Miroslav (203 Czech Republic, guarantor, belonging to the institution) and Eliška DASTYCHOVÁ (203 Czech Republic, belonging to the institution)

Edition

International Journal of Ophthalmology and Clinical Research, Wilmington, ClinMed International Library, 2017, 2378-346X

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Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30216 Dermatology and venereal diseases

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/17:00098829

Organization unit

Faculty of Medicine

Keywords in English

Periorbital dermatitis; Patch tests; Contact allergens

Tags

EL OK

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Abstract

V originále

Aims: 1) To determine actual frequency of sensitization to the most common contact allergens present in ophtalmic products. 2) To assess clinical relevance of the results and detect sources of sensitization. Methods: A total number of 1881 patients (mean age 46.5 years, 357 men, 1,524 women) with periorbital dermatitis underwent patch tested between the years 2001 and 2016 and were retrospectively enrolled into our study. Results: The highest frequency of sensitization was found with thimerosal (9.7%), followed by neomycin sulfate (2.6%), benzalkonium chloride (1.3%), and parabens (0.6%). In terms of clinical relevance however the most important allergen was neomycin sulfate. Conclusion: The most important allergens in ophtalmolog-ic products in our study were neomycin sulfate followed by benzalkonium chloride. With every case of periorbital dermatitis patch tests should be considered, not only with commercial test allergens but with patient's actual ophtalmic preparations as well.