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@article{1399365,
author = {Lewis, K.M. and Ruiz, M. and Goldblatt, P. and Morrison, J. and Porta, D. and Forastiere, F. and Hryhorczuk, D. and Zvinchuk, O. and SaurelandCubizolles, M.J. and Lioret, S. and AnnesiandMaesano, I. and Vrijheid, M. and Torrent, M. and Iniguez, C. and Larranaga, I. and Harskampandvan Ginkel, M.W. and Vrijkotte, T.G.M. and Klánová, Jana and Švancara, Jan and Barross, H. and Correia, S. and Jarvelin, M.R. and Taanila, A. and Ludvigsson, J. and Faresjo, T. and Marmot, M. and Pikhart, H.},
article_location = {Dordrecht Netherland},
article_number = {9},
doi = {http://dx.doi.org/10.1007/s10654-017-0309-0},
keywords = {Asthma; Children; Cohort studies; Maternal education; Socioeconomic position; Disease risk},
language = {eng},
issn = {0393-2990},
journal = {European Journal of Epidemiology},
title = {Mother's education and offspring asthma risk in 10 European cohort studies},
volume = {32},
year = {2017}
}
TY - JOUR
ID - 1399365
AU - Lewis, K.M. - Ruiz, M. - Goldblatt, P. - Morrison, J. - Porta, D. - Forastiere, F. - Hryhorczuk, D. - Zvinchuk, O. - Saurel-Cubizolles, M.J. - Lioret, S. - Annesi-Maesano, I. - Vrijheid, M. - Torrent, M. - Iniguez, C. - Larranaga, I. - Harskamp-van Ginkel, M.W. - Vrijkotte, T.G.M. - Klánová, Jana - Švancara, Jan - Barross, H. - Correia, S. - Jarvelin, M.R. - Taanila, A. - Ludvigsson, J. - Faresjo, T. - Marmot, M. - Pikhart, H.
PY - 2017
TI - Mother's education and offspring asthma risk in 10 European cohort studies
JF - European Journal of Epidemiology
VL - 32
IS - 9
SP - 797-805
EP - 797-805
PB - Kluwer Academic Publishers
SN - 03932990
KW - Asthma
KW - Children
KW - Cohort studies
KW - Maternal education
KW - Socioeconomic position
KW - Disease risk
N2 - Highly prevalent and typically beginning in childhood, asthma is a burdensome disease, yet the risk factors for this condition are not clarified. To enhance understanding, this study assessed the cohort-specific and pooled risk of maternal education on asthma in children aged 3-8 across 10 European countries. Data on 47,099 children were obtained from prospective birth cohort studies across 10 European countries. We calculated cohort-specific prevalence difference in asthma outcomes using the relative index of inequality (RII) and slope index of inequality (SII). Results from all countries were pooled using random-effects meta-analysis procedures to obtain mean RII and SII scores at the European level. Final models were adjusted for child sex, smoking during pregnancy, parity, mother's age and ethnicity. The higher the score the greater the magnitude of relative (RII, reference 1) and absolute (SII, reference 0) inequity. The pooled RII estimate for asthma risk across all cohorts was 1.46 (95% CI 1.26, 1.71) and the pooled SII estimate was 1.90 (95% CI 0.26, 3.54). Of the countries examined, France, the United Kingdom and the Netherlands had the highest prevalence's of childhood asthma and the largest inequity in asthma risk. Smaller inverse associations were noted for all other countries except Italy, which presented contradictory scores, but with small effect sizes. Tests for heterogeneity yielded significant results for SII scores. Overall, offspring of mothers with a low level of education had an increased relative and absolute risk of asthma compared to offspring of high-educated mothers.
ER -
LEWIS, K.M., M. RUIZ, P. GOLDBLATT, J. MORRISON, D. PORTA, F. FORASTIERE, D. HRYHORCZUK, O. ZVINCHUK, M.J. SAUREL-CUBIZOLLES, S. LIORET, I. ANNESI-MAESANO, M. VRIJHEID, M. TORRENT, C. INIGUEZ, I. LARRANAGA, M.W. HARSKAMP-VAN GINKEL, T.G.M. VRIJKOTTE, Jana KLÁNOVÁ, Jan ŠVANCARA, H. BARROSS, S. CORREIA, M.R. JARVELIN, A. TAANILA, J. LUDVIGSSON, T. FARESJO, M. MARMOT and H. PIKHART. Mother's education and offspring asthma risk in 10 European cohort studies. \textit{European Journal of Epidemiology}. Dordrecht Netherland: Kluwer Academic Publishers, vol.~32, No~9, p.~797-805. ISSN~0393-2990. doi:10.1007/s10654-017-0309-0. 2017.
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