Mother's education and offspring asthma risk in 10 European
cohort studies

J 2017

Mother's education and offspring asthma risk in 10 European cohort studies

LEWIS, K.M., M. RUIZ, P. GOLDBLATT, J. MORRISON, D. PORTA et. al.

Basic information

Original name

Mother's education and offspring asthma risk in 10 European cohort studies

Authors

LEWIS, K.M. (826 United Kingdom of Great Britain and Northern Ireland), M. RUIZ (826 United Kingdom of Great Britain and Northern Ireland), P. GOLDBLATT (826 United Kingdom of Great Britain and Northern Ireland), J. MORRISON (826 United Kingdom of Great Britain and Northern Ireland), D. PORTA (826 United Kingdom of Great Britain and Northern Ireland), F. FORASTIERE (380 Italy), D. HRYHORCZUK (840 United States of America), O. ZVINCHUK (804 Ukraine), M.J. SAUREL-CUBIZOLLES (380 Italy), S. LIORET (250 France), I. ANNESI-MAESANO (250 France), M. VRIJHEID (724 Spain), M. TORRENT (724 Spain), C. INIGUEZ (724 Spain), I. LARRANAGA (724 Spain), M.W. HARSKAMP-VAN GINKEL (528 Netherlands), T.G.M. VRIJKOTTE (528 Netherlands), Jana KLÁNOVÁ (203 Czech Republic, belonging to the institution), Jan ŠVANCARA (203 Czech Republic, guarantor, belonging to the institution), H. BARROSS (620 Portugal), S. CORREIA (620 Portugal), M.R. JARVELIN (826 United Kingdom of Great Britain and Northern Ireland), A. TAANILA (246 Finland), J. LUDVIGSSON (752 Sweden), T. FARESJO (752 Sweden), M. MARMOT (826 United Kingdom of Great Britain and Northern Ireland) and H. PIKHART (826 United Kingdom of Great Britain and Northern Ireland)

Edition

European Journal of Epidemiology, Dordrecht Netherland, Kluwer Academic Publishers, 2017, 0393-2990

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30304 Public and environmental health

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 7.023

RIV identification code

RIV/00216224:14110/17:00098839

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s10654-017-0309-0

UT WoS

000414156900007

Keywords in English

Asthma; Children; Cohort studies; Maternal education; Socioeconomic position; Disease risk

Abstract

V originále

Highly prevalent and typically beginning in childhood, asthma is a burdensome disease, yet the risk factors for this condition are not clarified. To enhance understanding, this study assessed the cohort-specific and pooled risk of maternal education on asthma in children aged 3-8 across 10 European countries. Data on 47,099 children were obtained from prospective birth cohort studies across 10 European countries. We calculated cohort-specific prevalence difference in asthma outcomes using the relative index of inequality (RII) and slope index of inequality (SII). Results from all countries were pooled using random-effects meta-analysis procedures to obtain mean RII and SII scores at the European level. Final models were adjusted for child sex, smoking during pregnancy, parity, mother's age and ethnicity. The higher the score the greater the magnitude of relative (RII, reference 1) and absolute (SII, reference 0) inequity. The pooled RII estimate for asthma risk across all cohorts was 1.46 (95% CI 1.26, 1.71) and the pooled SII estimate was 1.90 (95% CI 0.26, 3.54). Of the countries examined, France, the United Kingdom and the Netherlands had the highest prevalence's of childhood asthma and the largest inequity in asthma risk. Smaller inverse associations were noted for all other countries except Italy, which presented contradictory scores, but with small effect sizes. Tests for heterogeneity yielded significant results for SII scores. Overall, offspring of mothers with a low level of education had an increased relative and absolute risk of asthma compared to offspring of high-educated mothers.

Links

EF15_003/0000469, research and development project

Name: Cetocoen Plus

LM2015051, research and development project

Name: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX RI)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

LEWIS, K.M., M. RUIZ, P. GOLDBLATT, J. MORRISON, D. PORTA, F. FORASTIERE, D. HRYHORCZUK, O. ZVINCHUK, M.J. SAUREL-CUBIZOLLES, S. LIORET, I. ANNESI-MAESANO, M. VRIJHEID, M. TORRENT, C. INIGUEZ, I. LARRANAGA, M.W. HARSKAMP-VAN GINKEL, T.G.M. VRIJKOTTE, Jana KLÁNOVÁ, Jan ŠVANCARA, H. BARROSS, S. CORREIA, M.R. JARVELIN, A. TAANILA, J. LUDVIGSSON, T. FARESJO, M. MARMOT and H. PIKHART. Mother's education and offspring asthma risk in 10 European cohort studies. European Journal of Epidemiology. Dordrecht Netherland: Kluwer Academic Publishers, 2017, vol. 32, No 9, p. 797-805. ISSN 0393-2990. Available from: https://dx.doi.org/10.1007/s10654-017-0309-0.

@article{1399365,
   author = {Lewis, K.M. and Ruiz, M. and Goldblatt, P. and Morrison, J. and Porta, D. and Forastiere, F. and Hryhorczuk, D. and Zvinchuk, O. and SaurelandCubizolles, M.J. and Lioret, S. and AnnesiandMaesano, I. and Vrijheid, M. and Torrent, M. and Iniguez, C. and Larranaga, I. and Harskampandvan Ginkel, M.W. and Vrijkotte, T.G.M. and Klánová, Jana and Švancara, Jan and Barross, H. and Correia, S. and Jarvelin, M.R. and Taanila, A. and Ludvigsson, J. and Faresjo, T. and Marmot, M. and Pikhart, H.},
   article_location = {Dordrecht Netherland},
   article_number = {9},
   doi = {http://dx.doi.org/10.1007/s10654-017-0309-0},
   keywords = {Asthma; Children; Cohort studies; Maternal education; Socioeconomic position; Disease risk},
   language = {eng},
   issn = {0393-2990},
   journal = {European Journal of Epidemiology},
   title = {Mother's education and offspring asthma risk in 10 European cohort studies},
   volume = {32},
   year = {2017}
}

TY  - JOUR
ID  - 1399365
AU  - Lewis, K.M. - Ruiz, M. - Goldblatt, P. - Morrison, J. - Porta, D. - Forastiere, F. - Hryhorczuk, D. - Zvinchuk, O. - Saurel-Cubizolles, M.J. - Lioret, S. - Annesi-Maesano, I. - Vrijheid, M. - Torrent, M. - Iniguez, C. - Larranaga, I. - Harskamp-van Ginkel, M.W. - Vrijkotte, T.G.M. - Klánová, Jana - Švancara, Jan - Barross, H. - Correia, S. - Jarvelin, M.R. - Taanila, A. - Ludvigsson, J. - Faresjo, T. - Marmot, M. - Pikhart, H.
PY  - 2017
TI  - Mother's education and offspring asthma risk in 10 European cohort studies
JF  - European Journal of Epidemiology
VL  - 32
IS  - 9
SP  - 797-805
EP  - 797-805
PB  - Kluwer Academic Publishers
SN  - 03932990
KW  - Asthma
KW  - Children
KW  - Cohort studies
KW  - Maternal education
KW  - Socioeconomic position
KW  - Disease risk
N2  - Highly prevalent and typically beginning in childhood, asthma is a burdensome disease, yet the risk factors for this condition are not clarified. To enhance understanding, this study assessed the cohort-specific and pooled risk of maternal education on asthma in children aged 3-8 across 10 European countries. Data on 47,099 children were obtained from prospective birth cohort studies across 10 European countries. We calculated cohort-specific prevalence difference in asthma outcomes using the relative index of inequality (RII) and slope index of inequality (SII). Results from all countries were pooled using random-effects meta-analysis procedures to obtain mean RII and SII scores at the European level. Final models were adjusted for child sex, smoking during pregnancy, parity, mother's age and ethnicity. The higher the score the greater the magnitude of relative (RII, reference 1) and absolute (SII, reference 0) inequity. The pooled RII estimate for asthma risk across all cohorts was 1.46 (95% CI 1.26, 1.71) and the pooled SII estimate was 1.90 (95% CI 0.26, 3.54). Of the countries examined, France, the United Kingdom and the Netherlands had the highest prevalence's of childhood asthma and the largest inequity in asthma risk. Smaller inverse associations were noted for all other countries except Italy, which presented contradictory scores, but with small effect sizes. Tests for heterogeneity yielded significant results for SII scores. Overall, offspring of mothers with a low level of education had an increased relative and absolute risk of asthma compared to offspring of high-educated mothers.
ER  -

LEWIS, K.M., M. RUIZ, P. GOLDBLATT, J. MORRISON, D. PORTA, F. FORASTIERE, D. HRYHORCZUK, O. ZVINCHUK, M.J. SAUREL-CUBIZOLLES, S. LIORET, I. ANNESI-MAESANO, M. VRIJHEID, M. TORRENT, C. INIGUEZ, I. LARRANAGA, M.W. HARSKAMP-VAN GINKEL, T.G.M. VRIJKOTTE, Jana KLÁNOVÁ, Jan ŠVANCARA, H. BARROSS, S. CORREIA, M.R. JARVELIN, A. TAANILA, J. LUDVIGSSON, T. FARESJO, M. MARMOT and H. PIKHART. Mother's education and offspring asthma risk in 10 European cohort studies. \textit{European Journal of Epidemiology}. Dordrecht Netherland: Kluwer Academic Publishers, 2017, vol.~32, No~9, p.~797-805. ISSN~0393-2990. Available from: https://dx.doi.org/10.1007/s10654-017-0309-0.

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