a 2017

Cellular structural biology of nucleic acids

DŽATKO, Šimon, Michaela KRAFČÍKOVÁ, Radovan FIALA, Tomáš FESSL, Tomáš LOJA et. al.

Basic information

Original name

Cellular structural biology of nucleic acids

Authors

DŽATKO, Šimon (703 Slovakia, belonging to the institution), Michaela KRAFČÍKOVÁ (703 Slovakia, belonging to the institution), Radovan FIALA (203 Czech Republic, belonging to the institution), Tomáš FESSL (203 Czech Republic), Tomáš LOJA (703 Slovakia, belonging to the institution), C. CARON (250 France), A. GRANZHAN (250 France), M.P. TEULADE FICHOU (250 France), J.L. MERGNY (250 France), Silvie TRANTÍRKOVÁ (203 Czech Republic, belonging to the institution) and Lukáš TRANTÍREK (203 Czech Republic, guarantor, belonging to the institution)

Edition

42nd FEBS Congress, Jerusalem, Izrael, září 2017 in The FEBS Journal (2017), 2017

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

10608 Biochemistry and molecular biology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 4.530

RIV identification code

RIV/00216224:14740/17:00095290

Organization unit

Central European Institute of Technology

ISSN

UT WoS

000409918904245

Keywords in English

nucleic acids; DNA

Tags

Tags

International impact, Reviewed
Změněno: 18/3/2018 20:29, Mgr. Pavla Foltynová, Ph.D.

Abstract

V originále

The nucleic acid structure, particularly that of DNA, is sensitively modulated by non-specific physical and chemical environmental factors such as nucleic acids concentration, water activity, molecular crowding, viscosity, temperature, pH and/or concentration and nature of counter ions. Existence of environmentally promoted conformational polymorphism thus indicates that characterization of DNA structure, dynamics, and DNA-ligand/protein interactions should be ideally performed under native conditions in complex environment of living cells.

Links

GA16-10504S, research and development project
Name: Charakterizace struktury nukleových kyselin v komplexním prostředí živých buněk pomocí vysoce rozlišené NMR spektroskopie
Investor: Czech Science Foundation
LQ1601, research and development project
Name: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR